Wijnholds J - Search Results

1

Retinogenesis of the Human Fetal Retina: An Apical Polarity Perspective.

Quinn PMJ, Wijnholds J. Quinn PMJ, et al. Among authors: wijnholds j. Genes (Basel). 2019 Nov 29;10(12):987. doi: 10.3390/genes10120987. Genes (Basel). 2019. PMID: 31795518 Free PMC article. Review.

2

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.

Pellissier LP, Alves CH, Quinn PM, Vos RM, Tanimoto N, Lundvig DM, Dudok JJ, Hooibrink B, Richard F, Beck SC, Huber G, Sothilingam V, Garcia Garrido M, Le Bivic A, Seeliger MW, Wijnholds J. Pellissier LP, et al. Among authors: wijnholds j. PLoS Genet. 2013;9(12):e1003976. doi: 10.1371/journal.pgen.1003976. Epub 2013 Dec 5. PLoS Genet. 2013. PMID: 24339791 Free PMC article.

3

Gene therapy into photoreceptors and Müller glial cells restores retinal structure and function in CRB1 retinitis pigmentosa mouse models.

Pellissier LP, Quinn PM, Alves CH, Vos RM, Klooster J, Flannery JG, Heimel JA, Wijnholds J. Pellissier LP, et al. Among authors: wijnholds j. Hum Mol Genet. 2015 Jun 1;24(11):3104-18. doi: 10.1093/hmg/ddv062. Epub 2015 Feb 20. Hum Mol Genet. 2015. PMID: 25701872

4

The CRB1 Complex: Following the Trail of Crumbs to a Feasible Gene Therapy Strategy.

Quinn PM, Pellissier LP, Wijnholds J. Quinn PM, et al. Among authors: wijnholds j. Front Neurosci. 2017 Apr 5;11:175. doi: 10.3389/fnins.2017.00175. eCollection 2017. Front Neurosci. 2017. PMID: 28424578 Free PMC article. Review.

5

Production of iPS-Derived Human Retinal Organoids for Use in Transgene Expression Assays.

Quinn PM, Buck TM, Ohonin C, Mikkers HMM, Wijnholds J. Quinn PM, et al. Among authors: wijnholds j. Methods Mol Biol. 2018;1715:261-273. doi: 10.1007/978-1-4939-7522-8_19. Methods Mol Biol. 2018. PMID: 29188520

6

CRB2 in immature photoreceptors determines the superior-inferior symmetry of the developing retina to maintain retinal structure and function.

Quinn PM, Alves CH, Klooster J, Wijnholds J. Quinn PM, et al. Among authors: wijnholds j. Hum Mol Genet. 2018 Sep 15;27(18):3137-3153. doi: 10.1093/hmg/ddy194. Hum Mol Genet. 2018. PMID: 29893966

7

Loss of CRB2 in Müller glial cells modifies a CRB1-associated retinitis pigmentosa phenotype into a Leber congenital amaurosis phenotype.

Quinn PM, Mulder AA, Henrique Alves C, Desrosiers M, de Vries SI, Klooster J, Dalkara D, Koster AJ, Jost CR, Wijnholds J. Quinn PM, et al. Among authors: wijnholds j. Hum Mol Genet. 2019 Jan 1;28(1):105-123. doi: 10.1093/hmg/ddy337. Hum Mol Genet. 2019. PMID: 30239717

8

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5.

Quinn PM, Buck TM, Mulder AA, Ohonin C, Alves CH, Vos RM, Bialecka M, van Herwaarden T, van Dijk EHC, Talib M, Freund C, Mikkers HMM, Hoeben RC, Goumans MJ, Boon CJF, Koster AJ, Chuva de Sousa Lopes SM, Jost CR, Wijnholds J. Quinn PM, et al. Among authors: wijnholds j. Stem Cell Reports. 2019 May 14;12(5):906-919. doi: 10.1016/j.stemcr.2019.03.002. Epub 2019 Apr 4. Stem Cell Reports. 2019. PMID: 30956116 Free PMC article.

9

CRB2 Loss in Rod Photoreceptors Is Associated with Progressive Loss of Retinal Contrast Sensitivity.

Alves CH, Boon N, Mulder AA, Koster AJ, Jost CR, Wijnholds J. Alves CH, et al. Among authors: wijnholds j. Int J Mol Sci. 2019 Aug 21;20(17):4069. doi: 10.3390/ijms20174069. Int J Mol Sci. 2019. PMID: 31438467 Free PMC article.

10

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in Crb1.

Boon N, Alves CH, Mulder AA, Andriessen CA, Buck TM, Quinn PMJ, Vos RM, Koster AJ, Jost CR, Wijnholds J. Boon N, et al. Among authors: wijnholds j. Int J Mol Sci. 2021 Mar 30;22(7):3563. doi: 10.3390/ijms22073563. Int J Mol Sci. 2021. PMID: 33808129 Free PMC article.

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