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Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level.
Fischer J, Kleinau G, Rutz C, Zwanziger D, Khajavi N, Müller A, Rehders M, Brix K, Worth CL, Führer D, Krude H, Wiesner B, Schülein R, Biebermann H. Fischer J, et al. Among authors: wiesner b. Cell Mol Life Sci. 2018 Jun;75(12):2227-2239. doi: 10.1007/s00018-017-2728-1. Epub 2017 Dec 30. Cell Mol Life Sci. 2018. PMID: 29290039 Free PMC article.
New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.
Biebermann H, Winkler F, Handke D, Teichmann A, Gerling B, Cameron F, Eichhorst J, Grüters A, Wiesner B, Kühnen P, Krude H, Kleinau G. Biebermann H, et al. Among authors: wiesner b. J Clin Endocrinol Metab. 2012 Feb;97(2):E228-32. doi: 10.1210/jc.2011-2106. Epub 2011 Nov 23. J Clin Endocrinol Metab. 2012. PMID: 22112806
Live cell imaging of G protein-coupled receptors.
Teichmann A, Schmidt A, Wiesner B, Oksche A, Schülein R. Teichmann A, et al. Among authors: wiesner b. Methods Mol Biol. 2012;897:139-69. doi: 10.1007/978-1-61779-909-9_7. Methods Mol Biol. 2012. PMID: 22674164
Use of Kaede fusions to visualize recycling of G protein-coupled receptors.
Schmidt A, Wiesner B, Weisshart K, Schulz K, Furkert J, Lamprecht B, Rosenthal W, Schülein R. Schmidt A, et al. Among authors: wiesner b. Traffic. 2009 Jan;10(1):2-15. doi: 10.1111/j.1600-0854.2008.00843.x. Epub 2008 Oct 14. Traffic. 2009. PMID: 18939954 Free article.
The pseudo signal peptide of the corticotropin-releasing factor receptor type 2a decreases receptor expression and prevents Gi-mediated inhibition of adenylyl cyclase activity.
Schulz K, Rutz C, Westendorf C, Ridelis I, Vogelbein S, Furkert J, Schmidt A, Wiesner B, Schülein R. Schulz K, et al. Among authors: wiesner b. J Biol Chem. 2010 Oct 22;285(43):32878-32887. doi: 10.1074/jbc.M110.129627. Epub 2010 Aug 3. J Biol Chem. 2010. PMID: 20682782 Free PMC article.
240 results