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Pleiotropic effects of GIP on islet function involve osteopontin.
Lyssenko V, Eliasson L, Kotova O, Pilgaard K, Wierup N, Salehi A, Wendt A, Jonsson A, De Marinis YZ, Berglund LM, Taneera J, Balhuizen A, Hansson O, Osmark P, Dunér P, Brøns C, Stancáková A, Kuusisto J, Bugliani M, Saxena R, Ahlqvist E, Kieffer TJ, Tuomi T, Isomaa B, Melander O, Sonestedt E, Orho-Melander M, Nilsson P, Bonetti S, Bonadonna R, Miccoli R, Delprato S, Marchetti P, Madsbad S, Poulsen P, Vaag A, Laakso M, Gomez MF, Groop L. Lyssenko V, et al. Among authors: wierup n. Diabetes. 2011 Sep;60(9):2424-33. doi: 10.2337/db10-1532. Epub 2011 Aug 1. Diabetes. 2011. PMID: 21810601 Free PMC article.
CART is a novel islet regulatory peptide.
Wierup N, Sundler F. Wierup N, et al. Peptides. 2006 Aug;27(8):2031-6. doi: 10.1016/j.peptides.2006.02.011. Epub 2006 Jul 13. Peptides. 2006. PMID: 16842887 Review.
Beta-cell PDE3B regulates Ca2+-stimulated exocytosis of insulin.
Walz HA, Wierup N, Vikman J, Manganiello VC, Degerman E, Eliasson L, Holst LS. Walz HA, et al. Among authors: wierup n. Cell Signal. 2007 Jul;19(7):1505-13. doi: 10.1016/j.cellsig.2007.01.030. Epub 2007 Feb 12. Cell Signal. 2007. PMID: 17368848
DPP-4 inhibition improves glucose tolerance and increases insulin and GLP-1 responses to gastric glucose in association with normalized islet topography in mice with beta-cell-specific overexpression of human islet amyloid polypeptide.
Ahrén B, Winzell MS, Wierup N, Sundler F, Burkey B, Hughes TE. Ahrén B, et al. Among authors: wierup n. Regul Pept. 2007 Oct 4;143(1-3):97-103. doi: 10.1016/j.regpep.2007.03.008. Epub 2007 Apr 11. Regul Pept. 2007. PMID: 17482289
121 results