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The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity.
Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, Godbout C, Hancock MA, Arezzo JC, Ocal O, Rocha C, Olieric N, Hall A, Ding H, Bramoullé A, Annis MG, Zogopoulos G, Harran PG, Wilkie TM, Brekken RA, Siegel PM, Steinmetz MO, Shore GC, Brouhard GJ, Roulston A. Wieczorek M, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra159. doi: 10.1126/scitranslmed.aag1093. Sci Transl Med. 2016. PMID: 27856798 Free PMC article.
553 results