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Chorioamnionitis induces changes in ovine pulmonary endogenous epithelial stem/progenitor cells in utero.
Widowski H, Ophelders DRMG, van Leeuwen AJCN, Nikkels PGJ, Severens-Rijvers CAH, LaPointe VLS, Cleutjens JPM, Hütten MC, Kemp MW, Payne MS, Saito M, Usuda H, Newnham JP, Jobe AH, Kramer BW, Delhaas T, Wolfs TGAM, Reynaert NL. Widowski H, et al. Pediatr Res. 2021 Sep;90(3):549-558. doi: 10.1038/s41390-020-01204-9. Epub 2020 Oct 18. Pediatr Res. 2021. PMID: 33070161
Sequential Exposure to Antenatal Microbial Triggers Attenuates Alveolar Growth and Pulmonary Vascular Development and Impacts Pulmonary Epithelial Stem/Progenitor Cells.
Widowski H, Reynaert NL, Ophelders DRMG, Hütten MC, Nikkels PGJ, Severens-Rijvers CAH, Cleutjens JPM, Kemp MW, Newnham JP, Saito M, Usuda H, Payne MS, Jobe AH, Kramer BW, Delhaas T, Wolfs TGAM. Widowski H, et al. Front Med (Lausanne). 2021 Feb 22;8:614239. doi: 10.3389/fmed.2021.614239. eCollection 2021. Front Med (Lausanne). 2021. PMID: 33693012 Free PMC article.
Multipotent adult progenitor cells prevent functional impairment and improve development in inflammation driven detriment of preterm ovine lungs.
Neuen SML, Ophelders DRMG, Widowski H, Hütten MC, Brokken T, van Gorp C, Nikkels PGJ, Severens-Rijvers CAH, Sthijns MMJPE, van Blitterswijk CA, Troost FJ, LaPointe VLS, Jolani S, Seiler C, Pillow JJ, Delhaas T, Reynaert NL, Wolfs TGAM. Neuen SML, et al. Among authors: widowski h. Regen Ther. 2024 Mar 28;27:207-217. doi: 10.1016/j.reth.2024.03.014. eCollection 2024 Dec. Regen Ther. 2024. PMID: 38576851 Free PMC article.
Polymer film-based microwell array platform for long-term culture and research of human bronchial organoids.
Baptista D, Tahmasebi Birgani Z, Widowski H, Passanha F, Stylianidis V, Knoops K, Gubbins E, Iriondo C, Skarp KP, Rottier RJ, Wolfs TG, van Blitterswijk C, LaPointe V, Habibović P, Reynaert NL, Giselbrecht S, Truckenmüller R. Baptista D, et al. Among authors: widowski h. Mater Today Bio. 2023 Mar 14;19:100603. doi: 10.1016/j.mtbio.2023.100603. eCollection 2023 Apr. Mater Today Bio. 2023. PMID: 37009070 Free PMC article.
Acute Lung Functional and Airway Remodeling Effects of an Inhaled Highly Selective Phosphodiesterase 4 Inhibitor in Ventilated Preterm Lambs Exposed to Chorioamnionitis.
Hütten MC, Brokken T, Widowski H, Monaco T, Schneider JP, Fehrholz M, Ophelders D, Kramer BW, Kunzmann S. Hütten MC, et al. Among authors: widowski h. Pharmaceuticals (Basel). 2022 Dec 26;16(1):29. doi: 10.3390/ph16010029. Pharmaceuticals (Basel). 2022. PMID: 36678525 Free PMC article.