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An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.
Weisser NE, Sanches M, Escobar-Cabrera E, O'Toole J, Whalen E, Chan PWY, Wickman G, Abraham L, Choi K, Harbourne B, Samiotakis A, Rojas AH, Volkers G, Wong J, Atkinson CE, Baardsnes J, Worrall LJ, Browman D, Smith EE, Baichoo P, Cheng CW, Guedia J, Kang S, Mukhopadhyay A, Newhook L, Ohrn A, Raghunatha P, Zago-Schmitt M, Schrag JD, Smith J, Zwierzchowski P, Scurll JM, Fung V, Black S, Strynadka NCJ, Gold MR, Presta LG, Ng G, Dixit S. Weisser NE, et al. Among authors: wickman g. Nat Commun. 2023 Mar 13;14(1):1394. doi: 10.1038/s41467-023-37029-3. Nat Commun. 2023. PMID: 36914633 Free PMC article.
AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design.
Sanches M, D'Angelo I, Jaramillo M, Baardsnes J, Zwaagstra J, Schrag J, Schoenhofen I, Acchione M, Lawn S, Wickman G, Weisser N, Poon DKY, Ng G, Dixit S. Sanches M, et al. Among authors: wickman g. MAbs. 2020 Jan-Dec;12(1):1802188. doi: 10.1080/19420862.2020.1802188. MAbs. 2020. PMID: 32816577 Free PMC article.
Targeting activin receptor-like kinase 1 inhibits angiogenesis and tumorigenesis through a mechanism of action complementary to anti-VEGF therapies.
Hu-Lowe DD, Chen E, Zhang L, Watson KD, Mancuso P, Lappin P, Wickman G, Chen JH, Wang J, Jiang X, Amundson K, Simon R, Erbersdobler A, Bergqvist S, Feng Z, Swanson TA, Simmons BH, Lippincott J, Casperson GF, Levin WJ, Stampino CG, Shalinsky DR, Ferrara KW, Fiedler W, Bertolini F. Hu-Lowe DD, et al. Among authors: wickman g. Cancer Res. 2011 Feb 15;71(4):1362-73. doi: 10.1158/0008-5472.CAN-10-1451. Epub 2011 Jan 6. Cancer Res. 2011. PMID: 21212415 Free PMC article.
47 results