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Microphysiological model of PIK3CA-driven vascular malformations reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.
Aw WY, Cho C, Wang H, Cooper AH, Doherty EL, Rocco D, Huang SA, Kubik S, Whitworth CP, Armstrong R, Hickey AJ, Griffith B, Kutys ML, Blatt J, Polacheck WJ. Aw WY, et al. Among authors: whitworth cp. Sci Adv. 2023 Feb 15;9(7):eade8939. doi: 10.1126/sciadv.ade8939. Epub 2023 Feb 15. Sci Adv. 2023. PMID: 36791204 Free PMC article.
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
Sanz M, Weideman AMK, Ward AR, Clohosey ML, Garcia-Recio S, Selitsky SR, Mann BT, Iannone MA, Whitworth CP, Chitrakar A, Garrido C, Kirchherr J, Coffey AR, Tsai YH, Samir S, Xu Y, Copertino D, Bosque A, Jones BR, Parker JS, Hudgens MG, Goonetilleke N, Soriano-Sarabia N. Sanz M, et al. Among authors: whitworth cp. Front Immunol. 2023 Sep 6;14:1219250. doi: 10.3389/fimmu.2023.1219250. eCollection 2023. Front Immunol. 2023. PMID: 37744358 Free PMC article.
Aminobisphosphonates reactivate the latent reservoir in people living with HIV-1.
Sanz M, Weideman AMK, Ward AR, Clohosey ML, Garcia-Recio S, Selitsky SR, Mann BT, Iannone MA, Whitworth CP, Chitrakar A, Garrido C, Kirchherr J, Coffey AR, Tsai YH, Samir S, Xu Y, Copertino D, Bosque A, Jones BR, Parker JS, Hudgens MG, Goonetilleke N, Soriano-Sarabia N. Sanz M, et al. Among authors: whitworth cp. bioRxiv [Preprint]. 2023 Feb 7:2023.02.07.527421. doi: 10.1101/2023.02.07.527421. bioRxiv. 2023. PMID: 36798291 Free PMC article. Updated. Preprint.
γδ T cells: an immunotherapeutic approach for HIV cure strategies.
Garrido C, Clohosey ML, Whitworth CP, Hudgens M, Margolis DM, Soriano-Sarabia N. Garrido C, et al. Among authors: whitworth cp. JCI Insight. 2018 Jun 21;3(12):e120121. doi: 10.1172/jci.insight.120121. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925697 Free PMC article.