Whitfield TW - Search Results

1

A maternally programmed intergenerational mechanism enables male offspring to make piRNAs from Y-linked precursor RNAs in Drosophila.

Venkei ZG, Gainetdinov I, Bagci A, Starostik MR, Choi CP, Fingerhut JM, Chen P, Balsara C, Whitfield TW, Bell GW, Feng S, Jacobsen SE, Aravin AA, Kim JK, Zamore PD, Yamashita YM. Venkei ZG, et al. Among authors: whitfield tw. Nat Cell Biol. 2023 Oct;25(10):1495-1505. doi: 10.1038/s41556-023-01227-4. Epub 2023 Sep 18. Nat Cell Biol. 2023. PMID: 37723298 Free PMC article.

2

Synonymous Mutations at the Beginning of the Influenza A Virus Hemagglutinin Gene Impact Experimental Fitness.

Canale AS, Venev SV, Whitfield TW, Caffrey DR, Marasco WA, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Zeldovich KB, Wang JP, Bolon DNA. Canale AS, et al. Among authors: whitfield tw. J Mol Biol. 2018 Apr 13;430(8):1098-1115. doi: 10.1016/j.jmb.2018.02.009. Epub 2018 Feb 18. J Mol Biol. 2018. PMID: 29466705

3

Constrained Mutational Sampling of Amino Acids in HIV-1 Protease Evolution.

Boucher JI, Whitfield TW, Dauphin A, Nachum G, Hollins C, Zeldovich KB, Swanstrom R, Schiffer CA, Luban J, Bolon DNA. Boucher JI, et al. Among authors: whitfield tw. Mol Biol Evol. 2019 Apr 1;36(4):798-810. doi: 10.1093/molbev/msz022. Mol Biol Evol. 2019. PMID: 30721995 Free PMC article.

4

Characterizing Protein-Ligand Binding Using Atomistic Simulation and Machine Learning: Application to Drug Resistance in HIV-1 Protease.

Whitfield TW, Ragland DA, Zeldovich KB, Schiffer CA. Whitfield TW, et al. J Chem Theory Comput. 2020 Feb 11;16(2):1284-1299. doi: 10.1021/acs.jctc.9b00781. Epub 2020 Jan 16. J Chem Theory Comput. 2020. PMID: 31877249 Free PMC article.

5

Structural Basis of the Disorder in the Tandem Zinc Finger Domain of the RNA-Binding Protein Tristetraprolin.

Tavella D, Deveau LM, Whitfield TW, Massi F. Tavella D, et al. Among authors: whitfield tw. J Chem Theory Comput. 2016 Oct 11;12(10):4717-4725. doi: 10.1021/acs.jctc.6b00150. Epub 2016 Sep 9. J Chem Theory Comput. 2016. PMID: 27487322 Free PMC article.

6

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

Liu Y, Flamier A, Bell GW, Diao AJ, Whitfield TW, Wang HC, Wu Y, Schulte F, Friesen M, Guo R, Mitalipova M, Liu XS, Vos SM, Young RA, Jaenisch R. Liu Y, et al. Among authors: whitfield tw. Neuron. 2024 Apr 30:S0896-6273(24)00245-9. doi: 10.1016/j.neuron.2024.04.007. Online ahead of print. Neuron. 2024. PMID: 38697112

7

Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction.

Vaccaro K, Allen J, Whitfield TW, Maoz A, Reeves S, Velarde J, Yang D, Meglan A, Ribeiro J, Blandin J, Phan N, Bell GW, Hata AN, Weiskopf K. Vaccaro K, et al. Among authors: whitfield tw. J Clin Invest. 2024 Mar 14;134(9):e169315. doi: 10.1172/JCI169315. J Clin Invest. 2024. PMID: 38483480 Free PMC article.

8

SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection.

Richards A, Khalil A, Friesen M, Whitfield TW, Lungjangwa T, Gehrke L, Mooney D, Jaenisch R. Richards A, et al. Among authors: whitfield tw. bioRxiv [Preprint]. 2023 Aug 7:2023.08.06.552160. doi: 10.1101/2023.08.06.552160. bioRxiv. 2023. PMID: 37609322 Free PMC article. Preprint.

9

Targeted therapies prime oncogene-driven lung cancers for macrophage-mediated destruction.

Vaccaro K, Allen J, Whitfield TW, Maoz A, Reeves S, Velarde J, Yang D, Phan N, Bell GW, Hata AN, Weiskopf K. Vaccaro K, et al. Among authors: whitfield tw. bioRxiv [Preprint]. 2023 Mar 6:2023.03.03.531059. doi: 10.1101/2023.03.03.531059. bioRxiv. 2023. PMID: 36945559 Free PMC article. Updated. Preprint.

10

Fragile X Syndrome Patient-Derived Neurons Developing in the Mouse Brain Show FMR1-Dependent Phenotypes.

Krzisch MA, Wu H, Yuan B, Whitfield TW, Liu XS, Fu D, Garrett-Engele CM, Khalil AS, Lungjangwa T, Shih J, Chang AN, Warren S, Cacace A, Andrykovich KR, Rietjens RGJ, Wallace O, Sur M, Jain B, Jaenisch R. Krzisch MA, et al. Among authors: whitfield tw. Biol Psychiatry. 2023 Jan 1;93(1):71-81. doi: 10.1016/j.biopsych.2022.08.020. Epub 2022 Aug 28. Biol Psychiatry. 2023. PMID: 36372569

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