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Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, Schmidt NM, Amin OE, Gill US, Stegmann KA, Burton AR, Stephenson E, Reynolds G, Whelan M, Sanchez J, de Maeyer R, Thakker C, Suveizdyte K, Uddin I, Ortega-Prieto AM, Grant C, Froghi F, Fusai G, Lens S, Pérez-Del-Pulgar S, Al-Akkad W, Mazza G, Noursadeghi M, Akbar A, Kennedy PTF, Davidson BR, Prinz M, Chain BM, Haniffa M, Gilroy DW, Dorner M, Bengsch B, Schurich A, Maini MK. Pallett LJ, et al. Among authors: whelan m. Nature. 2023 Feb;614(7947):334-342. doi: 10.1038/s41586-022-05645-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697826
Blood transcriptional biomarkers of acute viral infection for detection of pre-symptomatic SARS-CoV-2 infection: a nested, case-control diagnostic accuracy study.
Gupta RK, Rosenheim J, Bell LC, Chandran A, Guerra-Assuncao JA, Pollara G, Whelan M, Artico J, Joy G, Kurdi H, Altmann DM, Boyton RJ, Maini MK, McKnight A, Lambourne J, Cutino-Moguel T, Manisty C, Treibel TA, Moon JC, Chain BM, Noursadeghi M; COVIDsortium Investigators. Gupta RK, et al. Among authors: whelan m. Lancet Microbe. 2021 Oct;2(10):e508-e517. doi: 10.1016/S2666-5247(21)00146-4. Epub 2021 Jul 6. Lancet Microbe. 2021. PMID: 34250515 Free PMC article.
Rapid synchronous type 1 IFN and virus-specific T cell responses characterize first wave non-severe SARS-CoV-2 infections.
Chandran A, Rosenheim J, Nageswaran G, Swadling L, Pollara G, Gupta RK, Burton AR, Guerra-Assunção JA, Woolston A, Ronel T, Pade C, Gibbons JM, Sanz-Magallon Duque De Estrada B, Robert de Massy M, Whelan M, Semper A, Brooks T, Altmann DM, Boyton RJ, McKnight Á, Captur G, Manisty C, Treibel TA, Moon JC, Tomlinson GS, Maini MK, Chain BM, Noursadeghi M; COVIDsortium Investigators. Chandran A, et al. Among authors: whelan m. Cell Rep Med. 2022 Mar 4;3(3):100557. doi: 10.1016/j.xcrm.2022.100557. eCollection 2022 Mar 15. Cell Rep Med. 2022. PMID: 35474751 Free PMC article.
Large clones of pre-existing T cells drive early immunity against SARS-COV-2 and LCMV infection.
Milighetti M, Peng Y, Tan C, Mark M, Nageswaran G, Byrne S, Ronel T, Peacock T, Mayer A, Chandran A, Rosenheim J, Whelan M, Yao X, Liu G, Felce SL, Dong T, Mentzer AJ, Knight JC, Balloux F, Greenstein E, Reich-Zeliger S, Pade C, Gibbons JM, Semper A, Brooks T, Otter A, Altmann DM, Boyton RJ, Maini MK, McKnight A, Manisty C, Treibel TA, Moon JC; COVIDsortium Investigators; Noursadeghi M, Chain B. Milighetti M, et al. Among authors: whelan m. iScience. 2023 Jun 16;26(6):106937. doi: 10.1016/j.isci.2023.106937. Epub 2023 May 22. iScience. 2023. PMID: 37275518 Free PMC article.
Evolution of enhanced innate immune evasion by SARS-CoV-2.
Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Hosmillo M, Fossati A, Ragazzini R, Jungreis I, Ummadi M, Rojc A, Turner J, Bischof ML, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hiatt J, Rosales R, McGovern BL, Jahun A, Fabius JM, White K, Goodfellow IG, Takeuchi Y, Bonfanti P, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Kellis M, Swaney DL, García-Sastre A, Jolly C, Towers GJ, Krogan NJ. Thorne LG, et al. Among authors: whelan mvx. Nature. 2022 Feb;602(7897):487-495. doi: 10.1038/s41586-021-04352-y. Epub 2021 Dec 23. Nature. 2022. PMID: 34942634 Free PMC article.
Publisher Correction: Evolution of enhanced innate immune evasion by SARS-CoV-2.
Thorne LG, Bouhaddou M, Reuschl AK, Zuliani-Alvarez L, Polacco B, Pelin A, Batra J, Whelan MVX, Hosmillo M, Fossati A, Ragazzini R, Jungreis I, Ummadi M, Rojc A, Turner J, Bischof ML, Obernier K, Braberg H, Soucheray M, Richards A, Chen KH, Harjai B, Memon D, Hiatt J, Rosales R, McGovern BL, Jahun A, Fabius JM, White K, Goodfellow IG, Takeuchi Y, Bonfanti P, Shokat K, Jura N, Verba K, Noursadeghi M, Beltrao P, Kellis M, Swaney DL, García-Sastre A, Jolly C, Towers GJ, Krogan NJ. Thorne LG, et al. Among authors: whelan mvx. Nature. 2022 Apr;604(7905):E14. doi: 10.1038/s41586-022-04653-w. Nature. 2022. PMID: 35332335 Free PMC article. No abstract available.
Evolution of enhanced innate immune suppression by SARS-CoV-2 Omicron subvariants.
Reuschl AK, Thorne LG, Whelan MVX, Ragazzini R, Furnon W, Cowton VM, De Lorenzo G, Mesner D, Turner JLE, Dowgier G, Bogoda N, Bonfanti P, Palmarini M, Patel AH, Jolly C, Towers GJ. Reuschl AK, et al. Among authors: whelan mvx. Nat Microbiol. 2024 Feb;9(2):451-463. doi: 10.1038/s41564-023-01588-4. Epub 2024 Jan 16. Nat Microbiol. 2024. PMID: 38228858 Free PMC article.
512 results