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Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands.
Allison SJ, Sadiq M, Baronou E, Cooper PA, Dunnill C, Georgopoulos NT, Latif A, Shepherd S, Shnyder SD, Stratford IJ, Wheelhouse RT, Willans CE, Phillips RM. Allison SJ, et al. Among authors: wheelhouse rt. Cancer Lett. 2017 Sep 10;403:98-107. doi: 10.1016/j.canlet.2017.04.041. Epub 2017 Jun 15. Cancer Lett. 2017. PMID: 28624622 Free article.
Minor structural modifications to alchemix influence mechanism of action and pharmacological activity.
Abdallah QM, Phillips RM, Johansson F, Helleday T, Cosentino L, Abdel-Rahman H, Etzad J, Wheelhouse RT, Kiakos K, Bingham JP, Hartley JA, Patterson LH, Pors K. Abdallah QM, et al. Among authors: wheelhouse rt. Biochem Pharmacol. 2012 Jun 1;83(11):1514-22. doi: 10.1016/j.bcp.2012.02.017. Epub 2012 Mar 1. Biochem Pharmacol. 2012. PMID: 22387433 Free article.
Ruthenium-Containing Linear Helicates and Mesocates with Tuneable p53-Selective Cytotoxicity in Colorectal Cancer Cells.
Allison SJ, Cooke D, Davidson FS, Elliott PIP, Faulkner RA, Griffiths HBS, Harper OJ, Hussain O, Owen-Lynch PJ, Phillips RM, Rice CR, Shepherd SL, Wheelhouse RT. Allison SJ, et al. Among authors: wheelhouse rt. Angew Chem Int Ed Engl. 2018 Jul 26;57(31):9799-9804. doi: 10.1002/anie.201805510. Epub 2018 Jul 3. Angew Chem Int Ed Engl. 2018. PMID: 29863754
Corrigendum to "Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands" [Canc. Lett. 403 (2017) 98-107].
Allison SJ, Sadiq M, Baronou E, Cooper PA, Dunnill C, Georgopoulos NT, Latif A, Shepherd S, Shnyder SD, Stratford IJ, Wheelhouse RT, Willans CE, Phillips RM. Allison SJ, et al. Among authors: wheelhouse rt. Cancer Lett. 2018 Sep 1;431:247. doi: 10.1016/j.canlet.2018.06.022. Epub 2018 Jun 19. Cancer Lett. 2018. PMID: 29934232 Free article. No abstract available.
The medicinal chemistry of imidazotetrazine prodrugs.
Moody CL, Wheelhouse RT. Moody CL, et al. Among authors: wheelhouse rt. Pharmaceuticals (Basel). 2014 Jul 10;7(7):797-838. doi: 10.3390/ph7070797. Pharmaceuticals (Basel). 2014. PMID: 25014631 Free PMC article.
30 results