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Piezo2 is the major transducer of mechanical forces for touch sensation in mice.
Ranade SS, Woo SH, Dubin AE, Moshourab RA, Wetzel C, Petrus M, Mathur J, Bégay V, Coste B, Mainquist J, Wilson AJ, Francisco AG, Reddy K, Qiu Z, Wood JN, Lewin GR, Patapoutian A. Ranade SS, et al. Among authors: wetzel c. Nature. 2014 Dec 4;516(7529):121-5. doi: 10.1038/nature13980. Nature. 2014. PMID: 25471886 Free PMC article.
A stomatin-domain protein essential for touch sensation in the mouse.
Wetzel C, Hu J, Riethmacher D, Benckendorff A, Harder L, Eilers A, Moshourab R, Kozlenkov A, Labuz D, Caspani O, Erdmann B, Machelska H, Heppenstall PA, Lewin GR. Wetzel C, et al. Nature. 2007 Jan 11;445(7124):206-9. doi: 10.1038/nature05394. Epub 2006 Dec 13. Nature. 2007. PMID: 17167420
Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity.
Wetzel C, Pifferi S, Picci C, Gök C, Hoffmann D, Bali KK, Lampe A, Lapatsina L, Fleischer R, Smith ES, Bégay V, Moroni M, Estebanez L, Kühnemund J, Walcher J, Specker E, Neuenschwander M, von Kries JP, Haucke V, Kuner R, Poulet JF, Schmoranzer J, Poole K, Lewin GR. Wetzel C, et al. Nat Neurosci. 2017 Feb;20(2):209-218. doi: 10.1038/nn.4454. Epub 2016 Dec 12. Nat Neurosci. 2017. PMID: 27941788
Stomatin and sensory neuron mechanotransduction.
Martinez-Salgado C, Benckendorff AG, Chiang LY, Wang R, Milenkovic N, Wetzel C, Hu J, Stucky CL, Parra MG, Mohandas N, Lewin GR. Martinez-Salgado C, et al. Among authors: wetzel c. J Neurophysiol. 2007 Dec;98(6):3802-8. doi: 10.1152/jn.00860.2007. Epub 2007 Oct 17. J Neurophysiol. 2007. PMID: 17942620 Free article.
GABA blocks pathological but not acute TRPV1 pain signals.
Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfinger L, Schrenk-Siemens K, Tappe-Theodor A, Wetzel C, Kuich PH, Gassmann M, Roggenkamp D, Bettler B, Lewin GR, Selbach M, Siemens J. Hanack C, et al. Among authors: wetzel c. Cell. 2015 Feb 12;160(4):759-770. doi: 10.1016/j.cell.2015.01.022. Cell. 2015. PMID: 25679765 Free article.
251 results