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Inhibition of Interleukin-23-Mediated Inflammation with a Novel Small Molecule Inverse Agonist of RORγt.
Gauld SB, Jacquet S, Gauvin D, Wallace C, Wang Y, McCarthy R, Goess C, Leys L, Huang S, Su Z, Edelmayer R, Wetter J, Salte K, McGaraughty SP, Argiriadi MA, Honore P, Luccarini JM, Bressac D, Desino K, Breinlinger E, Cusack K, Potin D, Kort ME, Masson PJ. Gauld SB, et al. Among authors: wetter j. J Pharmacol Exp Ther. 2019 Oct;371(1):208-218. doi: 10.1124/jpet.119.258046. Epub 2019 Aug 2. J Pharmacol Exp Ther. 2019. PMID: 31375639
Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Todorović V, Su Z, Putman CB, Kakavas SJ, Salte KM, McDonald HA, Wetter JB, Paulsboe SE, Sun Q, Gerstein CE, Medina L, Sielaff B, Sadhukhan R, Stockmann H, Richardson PL, Qiu W, Argiriadi MA, Henry RF, Herold JM, Shotwell JB, McGaraughty SP, Honore P, Gopalakrishnan SM, Sun CC, Scott VE. Todorović V, et al. Among authors: wetter jb. Sci Rep. 2019 Jun 24;9(1):9089. doi: 10.1038/s41598-019-45626-w. Sci Rep. 2019. PMID: 31235749 Free PMC article.
IL-36 receptor antagonistic antibodies inhibit inflammatory responses in preclinical models of psoriasiform dermatitis.
Su Z, Paulsboe S, Wetter J, Salte K, Kannan A, Mathew S, Horowitz A, Gerstein C, Namovic M, Todorović V, Seagal J, Edelmayer RM, Viner M, Rinaldi L, Zhou L, Leys L, Huang S, Wang L, Sadhukhan R, Honore P, McGaraughty S, Scott VE. Su Z, et al. Among authors: wetter j. Exp Dermatol. 2019 Feb;28(2):113-120. doi: 10.1111/exd.13841. Epub 2018 Dec 21. Exp Dermatol. 2019. PMID: 30417427
Cytokine induced 3-D organotypic psoriasis skin model demonstrates distinct roles for NF-κB and JAK pathways in disease pathophysiology.
Todorović V, McDonald HA, Hoover P, Wetter JB, Marinopoulos AE, Woody CL, Miller L, Finkielsztein A, Dunstan RW, Paller AS, Honore P, Getsios S, Scott VE. Todorović V, et al. Among authors: wetter jb. Exp Dermatol. 2022 Jul;31(7):1036-1047. doi: 10.1111/exd.14551. Epub 2022 Mar 7. Exp Dermatol. 2022. PMID: 35213752 Free PMC article.
Persistence of Inflammatory Phenotype in Residual Psoriatic Plaques in Patients on Effective Biologic Therapy.
Mashiko S, Edelmayer RM, Bi Y, Olson LM, Wetter JB, Wang J, Maari C, Saint-Cyr Proulx E, Kaimal V, Li X, Salte K, Garcet S, Kannan AK, Huang SM, Cao X, Liu Z, Krueger JG, Sarfati M, Bissonnette R, Smith KM. Mashiko S, et al. Among authors: wetter jb. J Invest Dermatol. 2020 May;140(5):1015-1025.e4. doi: 10.1016/j.jid.2019.09.027. Epub 2019 Nov 9. J Invest Dermatol. 2020. PMID: 31715177 Free article.
232 results