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β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Renz BW, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, Westphalen CB, Ilmer M, Valenti G, Mohanta SK, Habenicht AJR, Middelhoff M, Chu T, Nagar K, Tailor Y, Casadei R, Di Marco M, Kleespies A, Friedman RA, Remotti H, Reichert M, Worthley DL, Neumann J, Werner J, Iuga AC, Olive KP, Wang TC. Renz BW, et al. Among authors: westphalen cb. Cancer Cell. 2018 Jan 8;33(1):75-90.e7. doi: 10.1016/j.ccell.2017.11.007. Epub 2017 Dec 14. Cancer Cell. 2018. PMID: 29249692 Free PMC article.
Long-lived intestinal tuft cells serve as colon cancer-initiating cells.
Westphalen CB, Asfaha S, Hayakawa Y, Takemoto Y, Lukin DJ, Nuber AH, Brandtner A, Setlik W, Remotti H, Muley A, Chen X, May R, Houchen CW, Fox JG, Gershon MD, Quante M, Wang TC. Westphalen CB, et al. J Clin Invest. 2014 Mar;124(3):1283-95. doi: 10.1172/JCI73434. J Clin Invest. 2014. PMID: 24487592 Free PMC article.
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma.
Rhim AD, Oberstein PE, Thomas DH, Mirek ET, Palermo CF, Sastra SA, Dekleva EN, Saunders T, Becerra CP, Tattersall IW, Westphalen CB, Kitajewski J, Fernandez-Barrena MG, Fernandez-Zapico ME, Iacobuzio-Donahue C, Olive KP, Stanger BZ. Rhim AD, et al. Among authors: westphalen cb. Cancer Cell. 2014 Jun 16;25(6):735-47. doi: 10.1016/j.ccr.2014.04.021. Epub 2014 May 22. Cancer Cell. 2014. PMID: 24856585 Free PMC article.
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism.
Sureban SM, May R, Weygant N, Qu D, Chandrakesan P, Bannerman-Menson E, Ali N, Pantazis P, Westphalen CB, Wang TC, Houchen CW. Sureban SM, et al. Among authors: westphalen cb. Cancer Lett. 2014 Aug 28;351(1):151-61. doi: 10.1016/j.canlet.2014.05.011. Epub 2014 May 28. Cancer Lett. 2014. PMID: 24880079
133 results