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Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.
Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Among authors: west lj. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.
A versatile soluble siglec scaffold for sensitive and quantitative detection of glycan ligands.
Rodrigues E, Jung J, Park H, Loo C, Soukhtehzari S, Kitova EN, Mozaneh F, Daskhan G, Schmidt EN, Aghanya V, Sarkar S, Streith L, St Laurent CD, Nguyen L, Julien JP, West LJ, Williams KC, Klassen JS, Macauley MS. Rodrigues E, et al. Among authors: west lj. Nat Commun. 2020 Oct 9;11(1):5091. doi: 10.1038/s41467-020-18907-6. Nat Commun. 2020. PMID: 33037195 Free PMC article.
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Nguyen L, McCord KA, Bui DT, Bouwman KM, Kitova EN, Elaish M, Kumawat D, Daskhan GC, Tomris I, Han L, Chopra P, Yang TJ, Willows SD, Mason AL, Mahal LK, Lowary TL, West LJ, Hsu SD, Hobman T, Tompkins SM, Boons GJ, de Vries RP, Macauley MS, Klassen JS. Nguyen L, et al. Among authors: west lj. Nat Chem Biol. 2022 Jan;18(1):81-90. doi: 10.1038/s41589-021-00924-1. Epub 2021 Nov 9. Nat Chem Biol. 2022. PMID: 34754101
Chemical Basis for Qualitative and Quantitative Differences Between ABO Blood Groups and Subgroups: Implications for Organ Transplantation.
Jeyakanthan M, Tao K, Zou L, Meloncelli PJ, Lowary TL, Suzuki K, Boland D, Larsen I, Burch M, Shaw N, Beddows K, Addonizio L, Zuckerman W, Afzali B, Kim DH, Mengel M, Shapiro AM, West LJ. Jeyakanthan M, et al. Among authors: west lj. Am J Transplant. 2015 Oct;15(10):2602-15. doi: 10.1111/ajt.13328. Epub 2015 May 26. Am J Transplant. 2015. PMID: 26014598 Free article.
223 results