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Single-cell transcriptional diversity is a hallmark of developmental potential.
Gulati GS, Sikandar SS, Wesche DJ, Manjunath A, Bharadwaj A, Berger MJ, Ilagan F, Kuo AH, Hsieh RW, Cai S, Zabala M, Scheeren FA, Lobo NA, Qian D, Yu FB, Dirbas FM, Clarke MF, Newman AM. Gulati GS, et al. Among authors: wesche dj. Science. 2020 Jan 24;367(6476):405-411. doi: 10.1126/science.aax0249. Science. 2020. PMID: 31974247 Free PMC article.
Single cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors.
Segal JM, Kent D, Wesche DJ, Ng SS, Serra M, Oulès B, Kar G, Emerton G, Blackford SJI, Darmanis S, Miquel R, Luong TV, Yamamoto R, Bonham A, Jassem W, Heaton N, Vigilante A, King A, Sancho R, Teichmann S, Quake SR, Nakauchi H, Rashid ST. Segal JM, et al. Among authors: wesche dj. Nat Commun. 2019 Jul 26;10(1):3350. doi: 10.1038/s41467-019-11266-x. Nat Commun. 2019. PMID: 31350390 Free PMC article.
The histone chaperone CAF-1 safeguards somatic cell identity.
Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, Rathert P, Jude J, Ferrari F, Blanco A, Fellner M, Wenzel D, Zinner M, Vidal SE, Bell O, Stadtfeld M, Chang HY, Almouzni G, Lowe SW, Rinn J, Wernig M, Aravin A, Shi Y, Park PJ, Penninger JM, Zuber J, Hochedlinger K. Cheloufi S, et al. Among authors: wesche dj. Nature. 2015 Dec 10;528(7581):218-24. doi: 10.1038/nature15749. Nature. 2015. PMID: 26659182 Free PMC article.
NDFIP allows NEDD4/NEDD4L-induced AQP2 ubiquitination and degradation.
Trimpert C, Wesche D, de Groot T, Pimentel Rodriguez MM, Wong V, van den Berg DTM, Cheval L, Ariza CA, Doucet A, Stagljar I, Deen PMT. Trimpert C, et al. PLoS One. 2017 Sep 20;12(9):e0183774. doi: 10.1371/journal.pone.0183774. eCollection 2017. PLoS One. 2017. PMID: 28931009 Free PMC article.