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Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.
Smits R, Fischer S, Hiller A, Deuther-Conrad W, Wenzel B, Patt M, Cumming P, Steinbach J, Sabri O, Brust P, Hoepping A. Smits R, et al. Among authors: wenzel b. Bioorg Med Chem. 2014 Jan 15;22(2):804-12. doi: 10.1016/j.bmc.2013.12.011. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24369841
Distinctive in vivo kinetics of the new σ1 receptor ligands (R)-(+)- and (S)-(-)-18F-fluspidine in porcine brain.
Brust P, Deuther-Conrad W, Becker G, Patt M, Donat CK, Stittsworth S, Fischer S, Hiller A, Wenzel B, Dukic-Stefanovic S, Hesse S, Steinbach J, Wünsch B, Lever SZ, Sabri O. Brust P, et al. Among authors: wenzel b. J Nucl Med. 2014 Oct;55(10):1730-6. doi: 10.2967/jnumed.114.137562. Epub 2014 Jul 28. J Nucl Med. 2014. PMID: 25071097 Free article.
Synthesis, 18F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography.
Schröder S, Wenzel B, Deuther-Conrad W, Teodoro R, Egerland U, Kranz M, Scheunemann M, Höfgen N, Steinbach J, Brust P. Schröder S, et al. Among authors: wenzel b. Molecules. 2015 May 26;20(6):9591-615. doi: 10.3390/molecules20069591. Molecules. 2015. PMID: 26016549 Free PMC article.
New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure.
Barthel C, Sorger D, Deuther-Conrad W, Scheunemann M, Schweiger S, Jäckel P, Roghani A, Steinbach J, Schüürmann G, Sabri O, Brust P, Wenzel B. Barthel C, et al. Among authors: wenzel b. Eur J Med Chem. 2015 Jul 15;100:50-67. doi: 10.1016/j.ejmech.2015.05.033. Epub 2015 May 22. Eur J Med Chem. 2015. PMID: 26071858
A Promising PET Tracer for Imaging of α₇ Nicotinic Acetylcholine Receptors in the Brain: Design, Synthesis, and in Vivo Evaluation of a Dibenzothiophene-Based Radioligand.
Teodoro R, Scheunemann M, Deuther-Conrad W, Wenzel B, Fasoli FM, Gotti C, Kranz M, Donat CK, Patt M, Hillmer A, Zheng MQ, Peters D, Steinbach J, Sabri O, Huang Y, Brust P. Teodoro R, et al. Among authors: wenzel b. Molecules. 2015 Oct 9;20(10):18387-421. doi: 10.3390/molecules201018387. Molecules. 2015. PMID: 26473809 Free PMC article.
Development of a Novel Nonpeptidic (18)F-Labeled Radiotracer for in Vivo Imaging of Oxytocin Receptors with Positron Emission Tomography.
Wenzel B, Mollitor J, Deuther-Conrad W, Dukic-Stefanovic S, Kranz M, Vraka C, Teodoro R, Günther R, Donat CK, Ludwig FA, Fischer S, Smits R, Wadsak W, Mitterhauser M, Steinbach J, Hoepping A, Brust P. Wenzel B, et al. J Med Chem. 2016 Mar 10;59(5):1800-17. doi: 10.1021/acs.jmedchem.5b01080. Epub 2016 Feb 3. J Med Chem. 2016. PMID: 26796795
203 results