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Exome sequencing implicates an increased burden of rare potassium channel variants in the risk of drug-induced long QT interval syndrome.
Weeke P, Mosley JD, Hanna D, Delaney JT, Shaffer C, Wells QS, Van Driest S, Karnes JH, Ingram C, Guo Y, Shyr Y, Norris K, Kannankeril PJ, Ramirez AH, Smith JD, Mardis ER, Nickerson D, George AL Jr, Roden DM. Weeke P, et al. Among authors: wells qs. J Am Coll Cardiol. 2014 Apr 15;63(14):1430-7. doi: 10.1016/j.jacc.2014.01.031. Epub 2014 Feb 19. J Am Coll Cardiol. 2014. PMID: 24561134 Free PMC article.
Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.
Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM. Mosley JD, et al. Among authors: wells qs. PLoS One. 2013 Dec 12;8(12):e81503. doi: 10.1371/journal.pone.0081503. eCollection 2013. PLoS One. 2013. PMID: 24349080 Free PMC article.
Phenotype-Driven Plasma Biobanking Strategies and Methods.
Bowton EA, Collier SP, Wang X, Sutcliffe CB, Van Driest SL, Couch LJ, Herrera M, Jerome RN, Slebos RJ, Alborn WE, Liebler DC, McNaughton CD, Mernaugh RL, Wells QS, Brown NJ, Roden DM, Pulley JM. Bowton EA, et al. Among authors: wells qs. J Pers Med. 2015 May 14;5(2):140-52. doi: 10.3390/jpm5020140. J Pers Med. 2015. PMID: 26110578 Free PMC article.
Phenotype risk scores identify patients with unrecognized Mendelian disease patterns.
Bastarache L, Hughey JJ, Hebbring S, Marlo J, Zhao W, Ho WT, Van Driest SL, McGregor TL, Mosley JD, Wells QS, Temple M, Ramirez AH, Carroll R, Osterman T, Edwards T, Ruderfer D, Velez Edwards DR, Hamid R, Cogan J, Glazer A, Wei WQ, Feng Q, Brilliant M, Zhao ZJ, Cox NJ, Roden DM, Denny JC. Bastarache L, et al. Among authors: wells qs. Science. 2018 Mar 16;359(6381):1233-1239. doi: 10.1126/science.aal4043. Science. 2018. PMID: 29590070 Free PMC article.
Nicotine Metabolism-informed Care for Smoking Cessation: A Pilot Precision RCT.
Wells QS, Freiberg MS, Greevy RA Jr, Tyndale RF, Kundu S, Duncan MS, King S, Abney L, Scoville E, Beaulieu DB, Gatskie V, Tindle HA. Wells QS, et al. Nicotine Tob Res. 2018 Nov 15;20(12):1489-1496. doi: 10.1093/ntr/ntx235. Nicotine Tob Res. 2018. PMID: 29059367 Free PMC article. Clinical Trial.
Varicose Veins Reach New Heights.
Wells QS. Wells QS. Circulation. 2018 Dec 18;138(25):2881-2883. doi: 10.1161/CIRCULATIONAHA.118.037219. Circulation. 2018. PMID: 30566011 Free article. No abstract available.
Attitudes toward Precision Treatment of Smoking in the Southern Community Cohort Study.
Senft N, Sanderson M, Selove R, Blot WJ, King S, Gilliam K, Kundu S, Steinwandel M, Sternlieb SJ, Warren Andersen S, Friedman DL, Connors E, Fadden MK, Freiberg M, Wells QS, Canedo J, Tyndale RF, Young RP, Hopkins RJ, Tindle HA. Senft N, et al. Among authors: wells qs. Cancer Epidemiol Biomarkers Prev. 2019 Aug;28(8):1345-1352. doi: 10.1158/1055-9965.EPI-19-0179. Epub 2019 Jun 3. Cancer Epidemiol Biomarkers Prev. 2019. PMID: 31160346 Free PMC article.
150 results