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Targeting lipid nanoparticles to the blood brain barrier to ameliorate acute ischemic stroke.
Nong J, Glassman PM, Reyes-Esteves S, Descamps HC, Shuvaev VV, Kiseleva RY, Papp TE, Alameh MG, Tam YK, Mui BL, Omo-Lamai S, Zamora ME, Shuvaeva T, Arguiri E, Thaiss CA, Myerson JW, Weissman D, Kasner SE, Parhiz H, Muzykantov VR, Brenner JS, Marcos-Contreras OA. Nong J, et al. Among authors: weissman d. bioRxiv [Preprint]. 2023 Jun 13:2023.06.12.544645. doi: 10.1101/2023.06.12.544645. bioRxiv. 2023. PMID: 37398465 Free PMC article. Updated. Preprint.
The Regulation of Nucleic Acid Vaccine Responses by the Microbiome.
Johnson AMF, Hager K, Alameh MG, Van P, Potchen N, Mayer-Blackwell K, Fiore-Gartland A, Minot S, Lin PJC, Tam YK, Weissman D, Kublin JG. Johnson AMF, et al. Among authors: weissman d. bioRxiv [Preprint]. 2023 Feb 19:2023.02.18.529093. doi: 10.1101/2023.02.18.529093. bioRxiv. 2023. PMID: 36824851 Free PMC article. Updated. Preprint.
VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis.
Rizvi F, Lee YR, Diaz-Aragon R, So J, Florentino RM, Smith AR, Everton E, Ostrowska A, Jung K, Tam Y, Muramatsu H, Pardi N, Weissman D, Soto-Gutierrez A, Shin D, Gouon-Evans V. Rizvi F, et al. Among authors: weissman d. bioRxiv [Preprint]. 2023 Apr 18:2023.04.17.537186. doi: 10.1101/2023.04.17.537186. bioRxiv. 2023. PMID: 37131823 Free PMC article. Updated. Preprint.
Development of a nucleoside-modified mRNA vaccine against clade 2.3.4.4b H5 highly pathogenic avian influenza virus.
Furey C, Ye N, Kercher L, DeBeauchamp J, Crumpton JC, Jeevan T, Patton C, Franks J, Alameh MG, Fan SHY, Phan AT, Hunter CA, Webby RJ, Weissman D, Hensley SE. Furey C, et al. Among authors: weissman d. bioRxiv [Preprint]. 2023 Apr 30:2023.04.30.538854. doi: 10.1101/2023.04.30.538854. bioRxiv. 2023. PMID: 37162920 Free PMC article. Preprint.
Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
Nong J, Glassman PM, Shuvaev VV, Reyes-Esteves S, Descamps HC, Kiseleva RY, Papp TE, Alameh MG, Tam YK, Mui BL, Omo-Lamai S, Zamora ME, Shuvaeva T, Arguiri E, Gong X, Brysgel TV, Tan AW, Woolfork AG, Weljie A, Thaiss CA, Myerson JW, Weissman D, Kasner SE, Parhiz H, Muzykantov VR, Brenner JS, Marcos-Contreras OA. Nong J, et al. Among authors: weissman d. Mol Ther. 2024 May 1;32(5):1344-1358. doi: 10.1016/j.ymthe.2024.03.004. Epub 2024 Mar 7. Mol Ther. 2024. PMID: 38454606
mRNA-based therapeutics: looking beyond COVID-19 vaccines.
Parhiz H, Atochina-Vasserman EN, Weissman D. Parhiz H, et al. Among authors: weissman d. Lancet. 2024 Mar 23;403(10432):1192-1204. doi: 10.1016/S0140-6736(23)02444-3. Epub 2024 Mar 7. Lancet. 2024. PMID: 38461842 Review.
IL7 increases targeted lipid nanoparticle-mediated mRNA expression in T cells in vitro and in vivo by enhancing T cell protein translation.
Tilsed CM, Sadiq BA, Papp TE, Areesawangkit P, Kimura K, Noguera-Ortega E, Scholler J, Cerda N, Aghajanian H, Bot A, Mui B, Tam Y, Weissman D, June CH, Albelda SM, Parhiz H. Tilsed CM, et al. Among authors: weissman d. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2319856121. doi: 10.1073/pnas.2319856121. Epub 2024 Mar 21. Proc Natl Acad Sci U S A. 2024. PMID: 38513098 Free PMC article.
Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system.
Parhiz H, Shuvaev VV, Li Q, Papp TE, Akyianu AA, Shi R, Yadegari A, Shahnawaz H, Semple SC, Mui BL, Weissman D, Muzykantov VR, Glassman PM. Parhiz H, et al. Among authors: weissman d. Mol Ther Nucleic Acids. 2024 Mar 18;35(2):102175. doi: 10.1016/j.omtn.2024.102175. eCollection 2024 Jun 11. Mol Ther Nucleic Acids. 2024. PMID: 38576454 Free PMC article.
Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles.
Mu Z, Wiehe K, Saunders KO, Henderson R, Cain DW, Parks R, Martik D, Mansouri K, Edwards RJ, Newman A, Lu X, Xia SM, Bonsignori M, Montefiori D, Han Q, Venkatayogi S, Evangelous T, Wang Y, Rountree W, Tam Y, Barbosa C, Alam SM, Williams WB, Pardi N, Weissman D, Haynes BF. Mu Z, et al. Among authors: weissman d. bioRxiv [Preprint]. 2021 Aug 9:2021.08.09.455714. doi: 10.1101/2021.08.09.455714. bioRxiv. 2021. PMID: 34401876 Free PMC article. Preprint.
796 results