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The pathophysiology of sepsis and precision-medicine-based immunotherapy.
Giamarellos-Bourboulis EJ, Aschenbrenner AC, Bauer M, Bock C, Calandra T, Gat-Viks I, Kyriazopoulou E, Lupse M, Monneret G, Pickkers P, Schultze JL, van der Poll T, van de Veerdonk FL, Vlaar APJ, Weis S, Wiersinga WJ, Netea MG. Giamarellos-Bourboulis EJ, et al. Among authors: weis s. Nat Immunol. 2024 Jan;25(1):19-28. doi: 10.1038/s41590-023-01660-5. Epub 2024 Jan 2. Nat Immunol. 2024. PMID: 38168953 Review.
Tidy up - The unfolded protein response in sepsis.
Vivas W, Weis S. Vivas W, et al. Among authors: weis s. Front Immunol. 2022 Oct 20;13:980680. doi: 10.3389/fimmu.2022.980680. eCollection 2022. Front Immunol. 2022. PMID: 36341413 Free PMC article. Review.
Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial.
Thomas-Rüddel D, Bauer M, Moita LF, Helbig C, Schlattmann P, Ehler J, Rahmel T, Meybohm P, Gründling M, Schenk H, Köcher T, Brunkhorst FM, Gräler M, Heger AJ, Weis S; EPOS-1 study group; SepNetCriticalCare TrialsGroup. Thomas-Rüddel D, et al. Among authors: weis s. BMJ Open. 2024 Apr 22;14(4):e075158. doi: 10.1136/bmjopen-2023-075158. BMJ Open. 2024. PMID: 38653508 Free PMC article.
Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis.
Renieris G, Droggiti DE, Katrini K, Koufargyris P, Gkavogianni T, Karakike E, Antonakos N, Damoraki G, Karageorgos A, Sabracos L, Katsouda A, Jentho E, Weis S, Wang R, Bauer M, Szabo C, Platoni K, Kouloulias V, Papapetropoulos A, Giamarellos-Bourboulis EJ. Renieris G, et al. Among authors: weis s. PLoS Pathog. 2021 Mar 26;17(3):e1009473. doi: 10.1371/journal.ppat.1009473. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33770141 Free PMC article.
ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol.
Kotsaki A, Pickkers P, Bauer M, Calandra T, Lupse M, Wiersinga WJ, Meylan S, Bloos F, van der Poll T, Slim MA, van Mourik N, Müller MCA, van Vught L, Vlaar APJ, de Nooijer A, Bakkerus L, Weis S, Antonakos N, Netea MG, Giamarellos-Bourboulis EJ. Kotsaki A, et al. Among authors: weis s. BMJ Open. 2022 Dec 20;12(12):e067251. doi: 10.1136/bmjopen-2022-067251. BMJ Open. 2022. PMID: 36600424 Free PMC article.
Labile heme impairs hepatic microcirculation and promotes hepatic injury.
Englert FA, Seidel RA, Galler K, Gouveia Z, Soares MP, Neugebauer U, Clemens MG, Sponholz C, Heinemann SH, Pohnert G, Bauer M, Weis S. Englert FA, et al. Among authors: weis s. Arch Biochem Biophys. 2019 Sep 15;672:108075. doi: 10.1016/j.abb.2019.108075. Epub 2019 Aug 11. Arch Biochem Biophys. 2019. PMID: 31412260
632 results