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Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2.
Prokopenko D, Lee S, Hecker J, Mullin K, Morgan S, Katsumata Y; Alzheimer’s Disease Neuroimaging Initiative (ADNI); Weiner MW, Fardo DW, Laird N, Bertram L, Hide W, Lange C, Tanzi RE. Prokopenko D, et al. Among authors: weiner mw. Mol Psychiatry. 2022 Apr;27(4):1963-1969. doi: 10.1038/s41380-022-01475-0. Epub 2022 Mar 4. Mol Psychiatry. 2022. PMID: 35246634 Free PMC article.
Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans.
Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, Bertram L, Jack CR Jr, Weiner MW; Alzheimer's Disease Neuroimaging Initiative. Saykin AJ, et al. Among authors: weiner mw. Alzheimers Dement. 2010 May;6(3):265-73. doi: 10.1016/j.jalz.2010.03.013. Alzheimers Dement. 2010. PMID: 20451875 Free PMC article.
CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects.
Ewers M, Insel P, Jagust WJ, Shaw L, Trojanowski JQ, Aisen P, Petersen RC, Schuff N, Weiner MW; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Ewers M, et al. Among authors: weiner mw. Cereb Cortex. 2012 Sep;22(9):1993-2004. doi: 10.1093/cercor/bhr271. Epub 2011 Oct 29. Cereb Cortex. 2012. PMID: 22038908 Free PMC article.
Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks.
Ramanan VK, Kim S, Holohan K, Shen L, Nho K, Risacher SL, Foroud TM, Mukherjee S, Crane PK, Aisen PS, Petersen RC, Weiner MW, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Ramanan VK, et al. Among authors: weiner mw. Brain Imaging Behav. 2012 Dec;6(4):634-48. doi: 10.1007/s11682-012-9196-x. Brain Imaging Behav. 2012. PMID: 22865056 Free PMC article.
Cognitive reserve associated with FDG-PET in preclinical Alzheimer disease.
Ewers M, Insel PS, Stern Y, Weiner MW; Alzheimer's Disease Neuroimaging Initiative (ADNI). Ewers M, et al. Among authors: weiner mw. Neurology. 2013 Mar 26;80(13):1194-201. doi: 10.1212/WNL.0b013e31828970c2. Epub 2013 Mar 13. Neurology. 2013. PMID: 23486873 Free PMC article.
Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel.
Kim S, Swaminathan S, Inlow M, Risacher SL, Nho K, Shen L, Foroud TM, Petersen RC, Aisen PS, Soares H, Toledo JB, Shaw LM, Trojanowski JQ, Weiner MW, McDonald BC, Farlow MR, Ghetti B, Saykin AJ; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Kim S, et al. Among authors: weiner mw. PLoS One. 2013 Jul 23;8(7):e70269. doi: 10.1371/journal.pone.0070269. Print 2013. PLoS One. 2013. PMID: 23894628 Free PMC article.
A single nucleotide polymorphism associated with reduced alcohol intake in the RASGRF2 gene predicts larger cortical volumes but faster longitudinal ventricular expansion in the elderly.
Roussotte FF, Gutman BA, Hibar DP, Jahanshad N, Madsen SK, Jack CR Jr, Weiner MW, Thompson PM; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Roussotte FF, et al. Among authors: weiner mw. Front Aging Neurosci. 2013 Dec 19;5:93. doi: 10.3389/fnagi.2013.00093. eCollection 2013. Front Aging Neurosci. 2013. PMID: 24409144 Free PMC article.
Quantifying anatomical shape variations in neurological disorders.
Singh N, Fletcher PT, Preston JS, King RD, Marron JS, Weiner MW, Joshi S; Alzheimer’s Disease Neuroimaging Initiative (ADNI). Singh N, et al. Among authors: weiner mw. Med Image Anal. 2014 Apr;18(3):616-33. doi: 10.1016/j.media.2014.01.001. Epub 2014 Feb 11. Med Image Anal. 2014. PMID: 24667299 Free PMC article.
Serum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructure.
Warstadt NM, Dennis EL, Jahanshad N, Kohannim O, Nir TM, McMahon KL, de Zubicaray GI, Montgomery GW, Henders AK, Martin NG, Whitfield JB, Jack CR Jr, Bernstein MA, Weiner MW, Toga AW, Wright MJ, Thompson PM; Alzheimer's Disease Neuroimaging Initiative (ADNI). Warstadt NM, et al. Among authors: weiner mw. Neurobiol Aging. 2014 Nov;35(11):2504-2513. doi: 10.1016/j.neurobiolaging.2014.05.024. Epub 2014 Jun 2. Neurobiol Aging. 2014. PMID: 24997672 Free PMC article.
967 results