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Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
Pototschnig I, Feiler U, Diwoky C, Vesely PW, Rauchenwald T, Paar M, Bakiri L, Pajed L, Hofer P, Kashofer K, Sukhbaatar N, Schoiswohl G, Weichhart T, Hoefler G, Bock C, Pichler M, Wagner EF, Zechner R, Schweiger M. Pototschnig I, et al. Among authors: weichhart t. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):93-107. doi: 10.1002/jcsm.13109. Epub 2022 Nov 9. J Cachexia Sarcopenia Muscle. 2023. PMID: 36351437 Free PMC article.
Metabolic support by macrophages sustains colonic epithelial homeostasis.
Fritsch SD, Sukhbaatar N, Gonzales K, Sahu A, Tran L, Vogel A, Mazic M, Wilson JL, Forisch S, Mayr H, Oberle R, Weiszmann J, Brenner M, Vanhoutte R, Hofmann M, Pirnes-Karhu S, Magnes C, Kühnast T, Weckwerth W, Bock C, Klavins K, Hengstschläger M, Moissl-Eichinger C, Schabbauer G, Egger G, Pirinen E, Verhelst SHL, Weichhart T. Fritsch SD, et al. Among authors: weichhart t. Cell Metab. 2023 Nov 7;35(11):1931-1943.e8. doi: 10.1016/j.cmet.2023.09.010. Epub 2023 Oct 6. Cell Metab. 2023. PMID: 37804836 Free article.
R-ketorolac ameliorates cancer-associated cachexia and prolongs survival of tumour-bearing mice.
Chrysostomou SE, Eder S, Pototschnig I, Mayer AL, Derler M, Mussbacher M, Schauer S, Zhang D, Yan D, Liu G, Hoefler G, Weichhart T, Vesely PW, Zhang L, Schweiger M. Chrysostomou SE, et al. Among authors: weichhart t. J Cachexia Sarcopenia Muscle. 2024 Apr;15(2):562-574. doi: 10.1002/jcsm.13422. Epub 2024 Feb 1. J Cachexia Sarcopenia Muscle. 2024. PMID: 38302863 Free PMC article.
Single-cell and spatial transcriptomics reveal aberrant lymphoid developmental programs driving granuloma formation.
Krausgruber T, Redl A, Barreca D, Doberer K, Romanovskaia D, Dobnikar L, Guarini M, Unterluggauer L, Kleissl L, Atzmüller D, Mayerhofer C, Kopf A, Saluzzo S, Lim CX, Rexie P, Weichhart T, Bock C, Stary G. Krausgruber T, et al. Among authors: weichhart t. Immunity. 2023 Feb 14;56(2):289-306.e7. doi: 10.1016/j.immuni.2023.01.014. Epub 2023 Feb 6. Immunity. 2023. PMID: 36750099 Free PMC article.
Efficacy and safety of mTOR inhibition in cutaneous sarcoidosis: a single-centre trial.
Redl A, Doberer K, Unterluggauer L, Kleissl L, Krall C, Mayerhofer C, Reininger B, Stary V, Zila N, Weninger W, Weichhart T, Bock C, Krausgruber T, Stary G. Redl A, et al. Among authors: weichhart t. Lancet Rheumatol. 2024 Feb;6(2):e81-e91. doi: 10.1016/S2665-9913(23)00302-8. Lancet Rheumatol. 2024. PMID: 38267106 Clinical Trial.
Directions to overcome therapy resistance in cancer.
Nussinov R, Weichhart T, Dlamini Z, Gibbons DL, Van Seuningen I, Konen J, Ju HQ. Nussinov R, et al. Among authors: weichhart t. Trends Pharmacol Sci. 2024 May 16:S0165-6147(24)00093-2. doi: 10.1016/j.tips.2024.05.001. Online ahead of print. Trends Pharmacol Sci. 2024. PMID: 38760267 No abstract available.
97 results