Weibel DB - Search Results

1

Membrane-Targeting DCAP Analogues with Broad-Spectrum Antibiotic Activity against Pathogenic Bacteria.

Hurley KA, Heinrich VA, Hershfield JR, Demons ST, Weibel DB. Hurley KA, et al. Among authors: weibel db. ACS Med Chem Lett. 2015 Mar 1;6(4):466-71. doi: 10.1021/acsmedchemlett.5b00024. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 25941556 Free PMC article.

2

5-Alkyloxytryptamines are membrane-targeting, broad-spectrum antibiotics.

Faulkner KC, Hurley KA, Weibel DB. Faulkner KC, et al. Among authors: weibel db. Bioorg Med Chem Lett. 2016 Nov 15;26(22):5539-5544. doi: 10.1016/j.bmcl.2016.10.004. Epub 2016 Oct 5. Bioorg Med Chem Lett. 2016. PMID: 27765507 Free PMC article.

3

Targeting the Bacterial Division Protein FtsZ.

Hurley KA, Santos TM, Nepomuceno GM, Huynh V, Shaw JT, Weibel DB. Hurley KA, et al. Among authors: weibel db. J Med Chem. 2016 Aug 11;59(15):6975-98. doi: 10.1021/acs.jmedchem.5b01098. Epub 2016 Mar 10. J Med Chem. 2016. PMID: 26756351 Review.

4

Targeting quinolone- and aminocoumarin-resistant bacteria with new gyramide analogs that inhibit DNA gyrase.

Hurley KA, Santos TMA, Fensterwald MR, Rajendran M, Moore JT, Balmond EI, Blahnik BJ, Faulkner KC, Foss MH, Heinrich VA, Lammers MG, Moore LC, Reynolds GD, Shearn-Nance GP, Stearns BA, Yao ZW, Shaw JT, Weibel DB. Hurley KA, et al. Among authors: weibel db. Medchemcomm. 2017;8(5):942-951. doi: 10.1039/C7MD00012J. Epub 2017 Feb 27. Medchemcomm. 2017. PMID: 30034678 Free PMC article.

5

N-Benzyl-3-sulfonamidopyrrolidines are a New Class of Bacterial DNA Gyrase Inhibitors.

Foss MH, Hurley KA, Sorto N, Lackner LL, Thornton KM, Shaw JT, Weibel DB. Foss MH, et al. Among authors: weibel db. ACS Med Chem Lett. 2011 Apr 14;2(4):289-292. doi: 10.1021/ml1002822. ACS Med Chem Lett. 2011. PMID: 21552338 Free PMC article.

6

Gyramides prevent bacterial growth by inhibiting DNA gyrase and altering chromosome topology.

Rajendram M, Hurley KA, Foss MH, Thornton KM, Moore JT, Shaw JT, Weibel DB. Rajendram M, et al. Among authors: weibel db. ACS Chem Biol. 2014 Jun 20;9(6):1312-9. doi: 10.1021/cb500154m. Epub 2014 Apr 22. ACS Chem Biol. 2014. PMID: 24712739 Free PMC article.

7

DCAP: a broad-spectrum antibiotic that targets the cytoplasmic membrane of bacteria.

Eun YJ, Foss MH, Kiekebusch D, Pauw DA, Westler WM, Thanbichler M, Weibel DB. Eun YJ, et al. Among authors: weibel db. J Am Chem Soc. 2012 Jul 18;134(28):11322-5. doi: 10.1021/ja302542j. Epub 2012 Jul 5. J Am Chem Soc. 2012. PMID: 22741745 Free PMC article.

8

Structure-activity studies of divin: an inhibitor of bacterial cell division.

Zhou M, Eun YJ, Guzei IA, Weibel DB. Zhou M, et al. Among authors: weibel db. ACS Med Chem Lett. 2013 Sep 12;4(9):880-885. doi: 10.1021/ml400234x. ACS Med Chem Lett. 2013. PMID: 24044050 Free PMC article.

9

Encapsulating bacteria in agarose microparticles using microfluidics for high-throughput cell analysis and isolation.

Eun YJ, Utada AS, Copeland MF, Takeuchi S, Weibel DB. Eun YJ, et al. Among authors: weibel db. ACS Chem Biol. 2011 Mar 18;6(3):260-6. doi: 10.1021/cb100336p. Epub 2010 Dec 30. ACS Chem Biol. 2011. PMID: 21142208 Free PMC article.

10

Bacteria-surface interactions.

Tuson HH, Weibel DB. Tuson HH, et al. Among authors: weibel db. Soft Matter. 2013 May 14;9(18):4368-4380. doi: 10.1039/C3SM27705D. Soft Matter. 2013. PMID: 23930134 Free PMC article.

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