Wei W - Search Results

1

Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Zhang J, Bu X, Wang H, Zhu Y, Geng Y, Nihira NT, Tan Y, Ci Y, Wu F, Dai X, Guo J, Huang YH, Fan C, Ren S, Sun Y, Freeman GJ, Sicinski P, Wei W. Zhang J, et al. Among authors: wei w. Nature. 2018 Jan 4;553(7686):91-95. doi: 10.1038/nature25015. Epub 2017 Nov 16. Nature. 2018. PMID: 29160310 Free PMC article.

2

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex.

Wei W, Ayad NG, Wan Y, Zhang GJ, Kirschner MW, Kaelin WG Jr. Wei W, et al. Nature. 2004 Mar 11;428(6979):194-8. doi: 10.1038/nature02381. Nature. 2004. PMID: 15014503

3

Bioluminescent imaging of Cdk2 inhibition in vivo.

Zhang GJ, Safran M, Wei W, Sorensen E, Lassota P, Zhelev N, Neuberg DS, Shapiro G, Kaelin WG Jr. Zhang GJ, et al. Among authors: wei w. Nat Med. 2004 Jun;10(6):643-8. doi: 10.1038/nm1047. Epub 2004 May 2. Nat Med. 2004. PMID: 15122251

4

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit.

Binné UK, Classon MK, Dick FA, Wei W, Rape M, Kaelin WG Jr, Näär AM, Dyson NJ. Binné UK, et al. Among authors: wei w. Nat Cell Biol. 2007 Feb;9(2):225-32. doi: 10.1038/ncb1532. Epub 2006 Dec 24. Nat Cell Biol. 2007. PMID: 17187060

5

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction.

Gao D, Inuzuka H, Tseng A, Chin RY, Toker A, Wei W. Gao D, et al. Among authors: wei w. Nat Cell Biol. 2009 Apr;11(4):397-408. doi: 10.1038/ncb1847. Epub 2009 Mar 8. Nat Cell Biol. 2009. PMID: 19270695 Free PMC article.

6

SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.

Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W. Inuzuka H, et al. Among authors: wei w. Nature. 2011 Mar 3;471(7336):104-9. doi: 10.1038/nature09732. Nature. 2011. PMID: 21368833 Free PMC article.

7

Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis.

Liu P, Gan W, Inuzuka H, Lazorchak AS, Gao D, Arojo O, Liu D, Wan L, Zhai B, Yu Y, Yuan M, Kim BM, Shaik S, Menon S, Gygi SP, Lee TH, Asara JM, Manning BD, Blenis J, Su B, Wei W. Liu P, et al. Among authors: wei w. Nat Cell Biol. 2013 Nov;15(11):1340-50. doi: 10.1038/ncb2860. Epub 2013 Oct 27. Nat Cell Biol. 2013. PMID: 24161930 Free PMC article.

8

Dual phosphorylation of Sin1 at T86 and T398 negatively regulates mTORC2 complex integrity and activity.

Liu P, Guo J, Gan W, Wei W. Liu P, et al. Among authors: wei w. Protein Cell. 2014 Mar;5(3):171-7. doi: 10.1007/s13238-014-0021-8. Protein Cell. 2014. PMID: 24481632 Free PMC article.

9

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis.

Zhang J, Wan L, Dai X, Sun Y, Wei W. Zhang J, et al. Among authors: wei w. Biochim Biophys Acta. 2014 Apr;1845(2):277-93. doi: 10.1016/j.bbcan.2014.02.001. Epub 2014 Feb 22. Biochim Biophys Acta. 2014. PMID: 24569229 Free PMC article. Review.

10

Roles of F-box proteins in cancer.

Wang Z, Liu P, Inuzuka H, Wei W. Wang Z, et al. Among authors: wei w. Nat Rev Cancer. 2014 Apr;14(4):233-47. doi: 10.1038/nrc3700. Nat Rev Cancer. 2014. PMID: 24658274 Free PMC article. Review.

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