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Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.
Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Lee JD, et al. Among authors: wei j. Cell Rep. 2023 Dec 26;42(12):113478. doi: 10.1016/j.celrep.2023.113478. Epub 2023 Nov 21. Cell Rep. 2023. PMID: 37991919 Free PMC article.
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection.
Wei J, Alfajaro MM, DeWeirdt PC, Hanna RE, Lu-Culligan WJ, Cai WL, Strine MS, Zhang SM, Graziano VR, Schmitz CO, Chen JS, Mankowski MC, Filler RB, Ravindra NG, Gasque V, de Miguel FJ, Patil A, Chen H, Oguntuyo KY, Abriola L, Surovtseva YV, Orchard RC, Lee B, Lindenbach BD, Politi K, van Dijk D, Kadoch C, Simon MD, Yan Q, Doench JG, Wilen CB. Wei J, et al. Cell. 2021 Jan 7;184(1):76-91.e13. doi: 10.1016/j.cell.2020.10.028. Epub 2020 Oct 20. Cell. 2021. PMID: 33147444 Free PMC article.
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Wei J, Alfajaro MM, Shi Q, Mumbach MR, Limaye A, DeWeirdt PC, Schmitz CO, Parker KR, Woo E, Chang HY, Horvath TL, Carette JE, Bertozzi CR, Wilen CB, Satpathy AT. Flynn RA, et al. Among authors: wei j. Cell. 2021 Apr 29;184(9):2394-2411.e16. doi: 10.1016/j.cell.2021.03.012. Epub 2021 Mar 11. Cell. 2021. PMID: 33743211 Free PMC article.
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection.
Wei J, Patil A, Collings CK, Alfajaro MM, Liang Y, Cai WL, Strine MS, Filler RB, DeWeirdt PC, Hanna RE, Menasche BL, Ökten A, Peña-Hernández MA, Klein J, McNamara A, Rosales R, McGovern BL, Luis Rodriguez M, García-Sastre A, White KM, Qin Y, Doench JG, Yan Q, Iwasaki A, Zwaka TP, Qi J, Kadoch C, Wilen CB. Wei J, et al. Nat Genet. 2023 Mar;55(3):471-483. doi: 10.1038/s41588-023-01307-z. Epub 2023 Mar 9. Nat Genet. 2023. PMID: 36894709 Free PMC article.
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling.
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, Alfajaro MM, Wei J, Dong H, Homer RJ, Ring A, Wilen CB, Iwasaki A. Israelow B, et al. Among authors: wei j. bioRxiv [Preprint]. 2020 May 27:2020.05.27.118893. doi: 10.1101/2020.05.27.118893. bioRxiv. 2020. PMID: 32577647 Free PMC article. Updated. Preprint.
Systematic discovery and functional interrogation of SARS-CoV-2 viral RNA-host protein interactions during infection.
Flynn RA, Belk JA, Qi Y, Yasumoto Y, Schmitz CO, Mumbach MR, Limaye A, Wei J, Alfajaro MM, Parker KR, Chang HY, Horvath TL, Carette JE, Bertozzi C, Wilen CB, Satpathy AT. Flynn RA, et al. Among authors: wei j. bioRxiv [Preprint]. 2020 Oct 6:2020.10.06.327445. doi: 10.1101/2020.10.06.327445. bioRxiv. 2020. PMID: 33052334 Free PMC article. Updated. Preprint.
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells.
Chen JS, Chow RD, Song E, Mao T, Israelow B, Kamath K, Bozekowski J, Haynes WA, Filler RB, Menasche BL, Wei J, Alfajaro MM, Song W, Peng L, Carter L, Weinstein JS, Gowthaman U, Chen S, Craft J, Shon JC, Iwasaki A, Wilen CB, Eisenbarth SC. Chen JS, et al. Among authors: wei j. Sci Immunol. 2022 Feb 4;7(68):eabl5652. doi: 10.1126/sciimmunol.abl5652. Epub 2022 Feb 4. Sci Immunol. 2022. PMID: 34914544 Free PMC article.
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