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MYCN mediates cysteine addiction and sensitizes neuroblastoma to ferroptosis.
Alborzinia H, Flórez AF, Kreth S, Brückner LM, Yildiz U, Gartlgruber M, Odoni DI, Poschet G, Garbowicz K, Shao C, Klein C, Meier J, Zeisberger P, Nadler-Holly M, Ziehm M, Paul F, Burhenne J, Bell E, Shaikhkarami M, Würth R, Stainczyk SA, Wecht EM, Kreth J, Büttner M, Ishaque N, Schlesner M, Nicke B, Stresemann C, Llamazares-Prada M, Reiling JH, Fischer M, Amit I, Selbach M, Herrmann C, Wölfl S, Henrich KO, Höfer T, Trumpp A, Westermann F. Alborzinia H, et al. Among authors: wecht em. Nat Cancer. 2022 Apr;3(4):471-485. doi: 10.1038/s43018-022-00355-4. Epub 2022 Apr 28. Nat Cancer. 2022. PMID: 35484422 Free PMC article.
Super enhancers define regulatory subtypes and cell identity in neuroblastoma.
Gartlgruber M, Sharma AK, Quintero A, Dreidax D, Jansky S, Park YG, Kreth S, Meder J, Doncevic D, Saary P, Toprak UH, Ishaque N, Afanasyeva E, Wecht E, Koster J, Versteeg R, Grünewald TGP, Jones DTW, Pfister SM, Henrich KO, van Nes J, Herrmann C, Westermann F. Gartlgruber M, et al. Nat Cancer. 2021 Jan;2(1):114-128. doi: 10.1038/s43018-020-00145-w. Epub 2020 Dec 7. Nat Cancer. 2021. PMID: 35121888
Alternative lengthening of telomeres in childhood neuroblastoma from genome to proteome.
Hartlieb SA, Sieverling L, Nadler-Holly M, Ziehm M, Toprak UH, Herrmann C, Ishaque N, Okonechnikov K, Gartlgruber M, Park YG, Wecht EM, Savelyeva L, Henrich KO, Rosswog C, Fischer M, Hero B, Jones DTW, Pfaff E, Witt O, Pfister SM, Volckmann R, Koster J, Kiesel K, Rippe K, Taschner-Mandl S, Ambros P, Brors B, Selbach M, Feuerbach L, Westermann F. Hartlieb SA, et al. Among authors: wecht em. Nat Commun. 2021 Feb 24;12(1):1269. doi: 10.1038/s41467-021-21247-8. Nat Commun. 2021. PMID: 33627664 Free PMC article.