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Trapping the HIV-1 V3 loop in a helical conformation enables broad neutralization.
Glögl M, Friedrich N, Cerutti G, Lemmin T, Kwon YD, Gorman J, Maliqi L, Mittl PRE, Hesselman MC, Schmidt D, Weber J, Foulkes C, Dingens AS, Bylund T, Olia AS, Verardi R, Reinberg T, Baumann NS, Rusert P, Dreier B, Shapiro L, Kwong PD, Plückthun A, Trkola A. Glögl M, et al. Among authors: weber j. Nat Struct Mol Biol. 2023 Sep;30(9):1323-1336. doi: 10.1038/s41594-023-01062-z. Epub 2023 Aug 21. Nat Struct Mol Biol. 2023. PMID: 37605043 Free PMC article.
Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs.
Oberle CS, Joos B, Rusert P, Campbell NK, Beauparlant D, Kuster H, Weber J, Schenkel CD, Scherrer AU, Magnus C, Kouyos R, Rieder P, Niederöst B, Braun DL, Pavlovic J, Böni J, Yerly S, Klimkait T, Aubert V, Trkola A, Metzner KJ, Günthard HF; Swiss HIV Cohort Study (SHCS). Oberle CS, et al. Among authors: weber j. Retrovirology. 2016 Sep 5;13(1):62. doi: 10.1186/s12977-016-0299-0. Retrovirology. 2016. PMID: 27595568 Free PMC article.
Determinants of HIV-1 broadly neutralizing antibody induction.
Rusert P, Kouyos RD, Kadelka C, Ebner H, Schanz M, Huber M, Braun DL, Hozé N, Scherrer A, Magnus C, Weber J, Uhr T, Cippa V, Thorball CW, Kuster H, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Fellay J, Regoes RR, Günthard HF, Trkola A; Swiss HIV Cohort Study. Rusert P, et al. Among authors: weber j. Nat Med. 2016 Nov;22(11):1260-1267. doi: 10.1038/nm.4187. Epub 2016 Sep 26. Nat Med. 2016. PMID: 27668936
Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.
Beauparlant D, Rusert P, Magnus C, Kadelka C, Weber J, Uhr T, Zagordi O, Oberle C, Duenas-Decamp MJ, Clapham PR, Metzner KJ, Günthard HF, Trkola A. Beauparlant D, et al. Among authors: weber j. PLoS Pathog. 2017 Mar 6;13(3):e1006255. doi: 10.1371/journal.ppat.1006255. eCollection 2017 Mar. PLoS Pathog. 2017. PMID: 28264054 Free PMC article.
Distinct, IgG1-driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity.
Kadelka C, Liechti T, Ebner H, Schanz M, Rusert P, Friedrich N, Stiegeler E, Braun DL, Huber M, Scherrer AU, Weber J, Uhr T, Kuster H, Misselwitz B, Cavassini M, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Rauch A, Yerly S, Aubert V, Klimkait T, Böni J, Kouyos RD, Günthard HF, Trkola A; Swiss HIV Cohort Study. Kadelka C, et al. Among authors: weber j. J Exp Med. 2018 Jun 4;215(6):1589-1608. doi: 10.1084/jem.20180246. Epub 2018 May 24. J Exp Med. 2018. PMID: 29794117 Free PMC article.
5,104 results