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Dual IGF1R/IR inhibitors in combination with GD2-CAR T-cells display a potent anti-tumor activity in diffuse midline glioma H3K27M-mutant.
de Billy E, Pellegrino M, Orlando D, Pericoli G, Ferretti R, Businaro P, Ajmone-Cat MA, Rossi S, Petrilli LL, Maestro N, Diomedi-Camassei F, Pezzullo M, De Stefanis C, Bencivenga P, Palma A, Rota R, Del Bufalo F, Massimi L, Weber G, Jones C, Carai A, Caruso S, De Angelis B, Caruana I, Quintarelli C, Mastronuzzi A, Locatelli F, Vinci M. de Billy E, et al. Among authors: weber g. Neuro Oncol. 2022 Jul 1;24(7):1150-1163. doi: 10.1093/neuonc/noab300. Neuro Oncol. 2022. PMID: 34964902 Free PMC article.
Polymorphonuclear myeloid-derived suppressor cells impair the anti-tumor efficacy of GD2.CAR T-cells in patients with neuroblastoma.
Tumino N, Weber G, Besi F, Del Bufalo F, Bertaina V, Paci P, Quatrini L, Antonucci L, Sinibaldi M, Quintarelli C, Maggi E, De Angelis B, Locatelli F, Moretta L, Vacca P, Caruana I. Tumino N, et al. Among authors: weber g. J Hematol Oncol. 2021 Nov 12;14(1):191. doi: 10.1186/s13045-021-01193-0. J Hematol Oncol. 2021. PMID: 34772439 Free PMC article.
GD2 redirected CAR T and activated NK-cell-mediated secretion of IFNγ overcomes MYCN-dependent IDO1 inhibition, contributing to neuroblastoma cell immune escape.
Caforio M, Sorino C, Caruana I, Weber G, Camera A, Cifaldi L, De Angelis B, Del Bufalo F, Vitale A, Goffredo BM, De Vito R, Fruci D, Quintarelli C, Fanciulli M, Locatelli F, Folgiero V. Caforio M, et al. Among authors: weber g. J Immunother Cancer. 2021 Mar;9(3):e001502. doi: 10.1136/jitc-2020-001502. J Immunother Cancer. 2021. PMID: 33737337 Free PMC article.
Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas.
Arnone CM, Polito VA, Mastronuzzi A, Carai A, Diomedi FC, Antonucci L, Petrilli LL, Vinci M, Ferrari F, Salviato E, Scarsella M, De Stefanis C, Weber G, Quintarelli C, De Angelis B, Brenner MK, Gottschalk S, Hoyos V, Locatelli F, Caruana I, Del Bufalo F. Arnone CM, et al. Among authors: weber g. J Immunother Cancer. 2021 May;9(5):e001930. doi: 10.1136/jitc-2020-001930. J Immunother Cancer. 2021. PMID: 33963009 Free PMC article.
Choice of costimulatory domains and of cytokines determines CAR T-cell activity in neuroblastoma.
Quintarelli C, Orlando D, Boffa I, Guercio M, Polito VA, Petretto A, Lavarello C, Sinibaldi M, Weber G, Del Bufalo F, Giorda E, Scarsella M, Petrini S, Pagliara D, Locatelli F, De Angelis B, Caruana I. Quintarelli C, et al. Among authors: weber g. Oncoimmunology. 2018 Mar 15;7(6):e1433518. doi: 10.1080/2162402X.2018.1433518. eCollection 2018. Oncoimmunology. 2018. PMID: 29872565 Free PMC article.
Universal Ready-to-Use Immunotherapeutic Approach for the Treatment of Cancer: Expanded and Activated Polyclonal γδ Memory T Cells.
Polito VA, Cristantielli R, Weber G, Del Bufalo F, Belardinilli T, Arnone CM, Petretto A, Antonucci L, Giorda E, Tumino N, Pitisci A, De Angelis B, Quintarelli C, Locatelli F, Caruana I. Polito VA, et al. Among authors: weber g. Front Immunol. 2019 Nov 22;10:2717. doi: 10.3389/fimmu.2019.02717. eCollection 2019. Front Immunol. 2019. PMID: 31824502 Free PMC article.
Role of interferon-γ in immune-mediated graft failure after allogeneic hematopoietic stem cell transplantation.
Merli P, Caruana I, De Vito R, Strocchio L, Weber G, Del Bufalo F, Buatois V, Montanari P, Cefalo MG, Pitisci A, Algeri M, Galaverna F, Quintarelli C, Cirillo V, Pagliara D, Ferlin W, Ballabio M, De Min C, Locatelli F. Merli P, et al. Among authors: weber g. Haematologica. 2019 Nov;104(11):2314-2323. doi: 10.3324/haematol.2019.216101. Epub 2019 Feb 21. Haematologica. 2019. PMID: 30792213 Free PMC article.
Reversible induction of mitophagy by an optogenetic bimodular system.
D'Acunzo P, Strappazzon F, Caruana I, Meneghetti G, Di Rita A, Simula L, Weber G, Del Bufalo F, Dalla Valle L, Campello S, Locatelli F, Cecconi F. D'Acunzo P, et al. Among authors: weber g. Nat Commun. 2019 Apr 4;10(1):1533. doi: 10.1038/s41467-019-09487-1. Nat Commun. 2019. PMID: 30948710 Free PMC article.
2,576 results