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A first-in-human Phase I trial of the oral p-STAT3 inhibitor WP1066 in patients with recurrent malignant glioma.
Groot J, Ott M, Wei J, Kassab C, Fang D, Najem H, O'Brien B, Weathers SP, Matsouka CK, Majd NK, Harrison RA, Fuller GN, Huse JT, Long JP, Sawaya R, Rao G, MacDonald TJ, Priebe W, DeCuypere M, Heimberger AB. Groot J, et al. Among authors: weathers sp. CNS Oncol. 2022 Jun 1;11(2):CNS87. doi: 10.2217/cns-2022-0005. Epub 2022 May 16. CNS Oncol. 2022. PMID: 35575067 Free PMC article. Clinical Trial.
Immune checkpoint blockade as a potential therapeutic target: surveying CNS malignancies.
Garber ST, Hashimoto Y, Weathers SP, Xiu J, Gatalica Z, Verhaak RG, Zhou S, Fuller GN, Khasraw M, de Groot J, Reddy SK, Spetzler D, Heimberger AB. Garber ST, et al. Among authors: weathers sp. Neuro Oncol. 2016 Oct;18(10):1357-66. doi: 10.1093/neuonc/now132. Epub 2016 Jul 1. Neuro Oncol. 2016. PMID: 27370400 Free PMC article.
A randomized phase II trial of standard dose bevacizumab versus low dose bevacizumab plus lomustine (CCNU) in adults with recurrent glioblastoma.
Weathers SP, Han X, Liu DD, Conrad CA, Gilbert MR, Loghin ME, O'Brien BJ, Penas-Prado M, Puduvalli VK, Tremont-Lukats I, Colen RR, Yung WKA, de Groot JF. Weathers SP, et al. J Neurooncol. 2016 Sep;129(3):487-494. doi: 10.1007/s11060-016-2195-9. Epub 2016 Jul 12. J Neurooncol. 2016. PMID: 27406589 Free PMC article. Clinical Trial.
Tumor Vaccines for Malignant Gliomas.
Srinivasan VM, Ferguson SD, Lee S, Weathers SP, Kerrigan BCP, Heimberger AB. Srinivasan VM, et al. Among authors: weathers sp. Neurotherapeutics. 2017 Apr;14(2):345-357. doi: 10.1007/s13311-017-0522-2. Neurotherapeutics. 2017. PMID: 28389997 Free PMC article. Review.
Intracranial dural, calvarial, and skull base metastases.
Harrison RA, Nam JY, Weathers SP, DeMonte F. Harrison RA, et al. Among authors: weathers sp. Handb Clin Neurol. 2018;149:205-225. doi: 10.1016/B978-0-12-811161-1.00014-1. Handb Clin Neurol. 2018. PMID: 29307354 Review.
Prospective Clinical Sequencing of Adult Glioma.
Zheng S, Alfaro-Munoz K, Wei W, Wang X, Wang F, Eterovic AK, Shaw KRM, Meric-Bernstam F, Fuller GN, Chen K, Verhaak RG, Mills GB, Yung WKA, Weathers SP, de Groot JF. Zheng S, et al. Among authors: weathers sp. Mol Cancer Ther. 2019 May;18(5):991-1000. doi: 10.1158/1535-7163.MCT-18-1122. Epub 2019 Mar 29. Mol Cancer Ther. 2019. PMID: 30926639 Free PMC article.
Pre-surgical connectome features predict IDH status in diffuse gliomas.
Kesler SR, Harrison RA, Petersen ML, Rao V, Dyson H, Alfaro-Munoz K, Weathers SP, de Groot J. Kesler SR, et al. Among authors: weathers sp. Oncotarget. 2019 Nov 5;10(60):6484-6493. doi: 10.18632/oncotarget.27301. eCollection 2019 Nov 5. Oncotarget. 2019. PMID: 31741712 Free PMC article.
Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.
de Groot J, Penas-Prado M, Alfaro-Munoz K, Hunter K, Pei BL, O'Brien B, Weathers SP, Loghin M, Kamiya Matsouka C, Yung WKA, Mandel J, Wu J, Yuan Y, Zhou S, Fuller GN, Huse J, Rao G, Weinberg JS, Prabhu SS, McCutcheon IE, Lang FF, Ferguson SD, Sawaya R, Colen R, Yadav SS, Blando J, Vence L, Allison J, Sharma P, Heimberger AB. de Groot J, et al. Among authors: weathers sp. Neuro Oncol. 2020 Apr 15;22(4):539-549. doi: 10.1093/neuonc/noz185. Neuro Oncol. 2020. PMID: 31755915 Free PMC article.
46 results