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Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction.
Fujihara KM, Zhang BZ, Jackson TD, Ogunkola MO, Nijagal B, Milne JV, Sallman DA, Ang CS, Nikolic I, Kearney CJ, Hogg SJ, Cabalag CS, Sutton VR, Watt S, Fujihara AT, Trapani JA, Simpson KJ, Stojanovski D, Leimkühler S, Haupt S, Phillips WA, Clemons NJ. Fujihara KM, et al. Among authors: watt s. Sci Adv. 2022 Sep 16;8(37):eabm9427. doi: 10.1126/sciadv.abm9427. Epub 2022 Sep 14. Sci Adv. 2022. PMID: 36103522 Free PMC article.
Differential cleavage of viral polypeptides by allotypic variants of granzyme B skews immunity to mouse cytomegalovirus.
Sutton VR, Andoniou C, Leeming MG, House CM, Watt SV, Verschoor S, Ciccone A, Voskoboinik I, Degli-Esposti M, Trapani JA. Sutton VR, et al. Among authors: watt sv. Biochim Biophys Acta Proteins Proteom. 2020 Sep;1868(9):140457. doi: 10.1016/j.bbapap.2020.140457. Epub 2020 May 27. Biochim Biophys Acta Proteins Proteom. 2020. PMID: 32473350
A role for granzyme M in TLR4-driven inflammation and endotoxicosis.
Anthony DA, Andrews DM, Chow M, Watt SV, House C, Akira S, Bird PI, Trapani JA, Smyth MJ. Anthony DA, et al. Among authors: watt sv. J Immunol. 2010 Aug 1;185(3):1794-803. doi: 10.4049/jimmunol.1000430. Epub 2010 Jun 28. J Immunol. 2010. PMID: 20585036
NK cell intrinsic regulation of MIP-1α by granzyme M.
Baschuk N, Wang N, Watt SV, Halse H, House C, Bird PI, Strugnell R, Trapani JA, Smyth MJ, Andrews DM. Baschuk N, et al. Among authors: watt sv. Cell Death Dis. 2014 Mar 13;5(3):e1115. doi: 10.1038/cddis.2014.74. Cell Death Dis. 2014. PMID: 24625974 Free PMC article.
Recognition of the nonclassical MHC class I molecule H2-M3 by the receptor Ly49A regulates the licensing and activation of NK cells.
Andrews DM, Sullivan LC, Baschuk N, Chan CJ, Berry R, Cotterell CL, Lin J, Halse H, Watt SV, Poursine-Laurent J, Wang CR, Scalzo AA, Yokoyama WM, Rossjohn J, Brooks AG, Smyth MJ. Andrews DM, et al. Nat Immunol. 2012 Dec;13(12):1171-7. doi: 10.1038/ni.2468. Epub 2012 Nov 11. Nat Immunol. 2012. PMID: 23142773 Free PMC article.
Asymmetric cell division of T cells upon antigen presentation uses multiple conserved mechanisms.
Oliaro J, Van Ham V, Sacirbegovic F, Pasam A, Bomzon Z, Pham K, Ludford-Menting MJ, Waterhouse NJ, Bots M, Hawkins ED, Watt SV, Cluse LA, Clarke CJ, Izon DJ, Chang JT, Thompson N, Gu M, Johnstone RW, Smyth MJ, Humbert PO, Reiner SL, Russell SM. Oliaro J, et al. J Immunol. 2010 Jul 1;185(1):367-75. doi: 10.4049/jimmunol.0903627. Epub 2010 Jun 7. J Immunol. 2010. PMID: 20530266 Free PMC article.
556 results