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873 results

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OpenFold: retraining AlphaFold2 yields new insights into its learning mechanisms and capacity for generalization.
Ahdritz G, Bouatta N, Floristean C, Kadyan S, Xia Q, Gerecke W, O'Donnell TJ, Berenberg D, Fisk I, Zanichelli N, Zhang B, Nowaczynski A, Wang B, Stepniewska-Dziubinska MM, Zhang S, Ojewole A, Guney ME, Biderman S, Watkins AM, Ra S, Lorenzo PR, Nivon L, Weitzner B, Ban YA, Chen S, Zhang M, Li C, Song SL, He Y, Sorger PK, Mostaque E, Zhang Z, Bonneau R, AlQuraishi M. Ahdritz G, et al. Among authors: watkins am. Nat Methods. 2024 May 14. doi: 10.1038/s41592-024-02272-z. Online ahead of print. Nat Methods. 2024. PMID: 38744917
Evaluation of different models of general practitioners working in or alongside emergency departments: a mixed-methods realist evaluation.
Davies F, Edwards M, Price D, Anderson P, Carson-Stevens A, Choudhry M, Cooke M, Dale J, Donaldson L, Evans BA, Harrington B, Harris S, Hepburn J, Hibbert P, Hughes T, Hussain F, Islam S, Pockett R, Porter A, Siriwardena AN, Snooks H, Watkins A, Edwards A, Cooper A. Davies F, et al. Among authors: watkins a. Health Soc Care Deliv Res. 2024 Apr;12(10):1-152. doi: 10.3310/JWQZ5348. Health Soc Care Deliv Res. 2024. PMID: 38687611
Programme theories to describe how different general practitioner service models work in different contexts in or alongside emergency departments (GP-ED): realist evaluation.
Cooper A, Edwards M, Davies F, Price D, Anderson P, Carson-Stevens A, Cooke M, Dale J, Donaldson L, Evans BA, Harrington B, Hepburn J, Hibbert P, Hughes TC, Porter A, Siriwardena AN, Watkins A, Snooks H, Edwards A. Cooper A, et al. Among authors: watkins a. Emerg Med J. 2024 Apr 22;41(5):287-295. doi: 10.1136/emermed-2023-213426. Emerg Med J. 2024. PMID: 38649248 Free PMC article.
Minimally Invasive Approaches to Mitral Valve Surgery: Where Are We Now? A Narrative Review.
El-Andari R, Watkins AR, Fialka NM, Kang JJ, Bozso SJ, Hassanabad AF, Vasanthan V, Adams C, Cook R, Moon MC, Nagendran J, Kent W; Western Canadian – Minimally Invasive Cardiac Surgery Working group. El-Andari R, et al. Among authors: watkins ar. Can J Cardiol. 2024 Mar 27:S0828-282X(24)00280-0. doi: 10.1016/j.cjca.2024.03.017. Online ahead of print. Can J Cardiol. 2024. PMID: 38552791 Review.
Discovery of Pyridopyrimidinones that Selectively Inhibit the H1047R PI3Kα Mutant Protein.
Ketcham JM, Harwood SJ, Aranda R, Aloiau AN, Bobek BM, Briere DM, Burns AC, Caddell Haatveit K, Calinisan A, Clarine J, Elliott A, Engstrom LD, Gunn RJ, Ivetac A, Jones B, Kuehler J, Lawson JD, Nguyen N, Parker C, Pearson KE, Rahbaek L, Saechao B, Wang X, Waters A, Waters L, Watkins AH, Olson P, Smith CR, Christensen JG, Marx MA. Ketcham JM, et al. Among authors: watkins ah. J Med Chem. 2024 Mar 28;67(6):4936-4949. doi: 10.1021/acs.jmedchem.4c00078. Epub 2024 Mar 13. J Med Chem. 2024. PMID: 38477582 Free PMC article.
873 results