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Membrane-bound mRNA immunogens lower the threshold to activate HIV Env V2 apex-directed broadly neutralizing B cell precursors in humanized mice.
Melzi E, Willis JR, Ma KM, Lin YC, Kratochvil S, Berndsen ZT, Landais EA, Kalyuzhniy O, Nair U, Warner J, Steichen JM, Kalyuzhniy A, Le A, Pecetta S, Perez M, Kirsch K, Weldon SR, Falcone S, Himansu S, Carfi A, Sok D, Ward AB, Schief WR, Batista FD. Melzi E, et al. Among authors: warner j. Immunity. 2022 Nov 8;55(11):2168-2186.e6. doi: 10.1016/j.immuni.2022.09.003. Epub 2022 Sep 29. Immunity. 2022. PMID: 36179690 Free PMC article.
Multiplexed CRISPR/CAS9-mediated engineering of pre-clinical mouse models bearing native human B cell receptors.
Wang X, Ray R, Kratochvil S, Melzi E, Lin YC, Giguere S, Xu L, Warner J, Cheon D, Liguori A, Groschel B, Phelps N, Adachi Y, Tingle R, Wu L, Crotty S, Kirsch KH, Nair U, Schief WR, Batista FD. Wang X, et al. Among authors: warner j. EMBO J. 2021 Jan 15;40(2):e105926. doi: 10.15252/embj.2020105926. Epub 2020 Dec 1. EMBO J. 2021. PMID: 33258500 Free PMC article.
Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.
Kratochvil S, Shen CH, Lin YC, Xu K, Nair U, Da Silva Pereira L, Tripathi P, Arnold J, Chuang GY, Melzi E, Schön A, Zhang B, Dillon M, Bonilla B, Flynn BJ, Kirsch KH, Kisalu NK, Kiyuka PK, Liu T, Ou L, Pancera M, Rawi R, Reveiz M, Seignon K, Wang LT, Waring MT, Warner J, Yang Y, Francica JR, Idris AH, Seder RA, Kwong PD, Batista FD. Kratochvil S, et al. Among authors: warner j. Immunity. 2021 Dec 14;54(12):2859-2876.e7. doi: 10.1016/j.immuni.2021.10.017. Epub 2021 Nov 16. Immunity. 2021. PMID: 34788599 Free PMC article.
Antibodies from primary humoral responses modulate the recruitment of naive B cells during secondary responses.
Tas JMJ, Koo JH, Lin YC, Xie Z, Steichen JM, Jackson AM, Hauser BM, Wang X, Cottrell CA, Torres JL, Warner JE, Kirsch KH, Weldon SR, Groschel B, Nogal B, Ozorowski G, Bangaru S, Phelps N, Adachi Y, Eskandarzadeh S, Kubitz M, Burton DR, Lingwood D, Schmidt AG, Nair U, Ward AB, Schief WR, Batista FD. Tas JMJ, et al. Among authors: warner je. Immunity. 2022 Oct 11;55(10):1856-1871.e6. doi: 10.1016/j.immuni.2022.07.020. Epub 2022 Aug 4. Immunity. 2022. PMID: 35987201 Free PMC article.
Travel-Time Disparities in Access to Proton Beam Therapy for Cancer Treatment.
Burus T, VanHelene AD, Rooney MK, Lang Kuhs KA, Christian WJ, McNair C, Mishra S, Paulino AC, Smith GL, Frank SJ, Warner JL. Burus T, et al. Among authors: warner jl. JAMA Netw Open. 2024 May 1;7(5):e2410670. doi: 10.1001/jamanetworkopen.2024.10670. JAMA Netw Open. 2024. PMID: 38758559 Free PMC article.
mRNA-LNP prime boost evolves precursors toward VRC01-like broadly neutralizing antibodies in preclinical humanized mouse models.
Wang X, Cottrell CA, Hu X, Ray R, Bottermann M, Villavicencio PM, Yan Y, Xie Z, Warner JE, Ellis-Pugh JR, Kalyuzhniy O, Liguori A, Willis JR, Menis S, Rämisch S, Eskandarzadeh S, Kubitz M, Tingle R, Phelps N, Groschel B, Himansu S, Carfi A, Kirsch KH, Weldon SR, Nair U, Schief WR, Batista FD. Wang X, et al. Among authors: warner je. Sci Immunol. 2024 May 10;9(95):eadn0622. doi: 10.1126/sciimmunol.adn0622. Epub 2024 May 16. Sci Immunol. 2024. PMID: 38753808
mRNA-LNP HIV-1 trimer boosters elicit precursors to broad neutralizing antibodies.
Xie Z, Lin YC, Steichen JM, Ozorowski G, Kratochvil S, Ray R, Torres JL, Liguori A, Kalyuzhniy O, Wang X, Warner JE, Weldon SR, Dale GA, Kirsch KH, Nair U, Baboo S, Georgeson E, Adachi Y, Kubitz M, Jackson AM, Richey ST, Volk RM, Lee JH, Diedrich JK, Prum T, Falcone S, Himansu S, Carfi A, Yates JR 3rd, Paulson JC, Sok D, Ward AB, Schief WR, Batista FD. Xie Z, et al. Among authors: warner je. Science. 2024 May 17;384(6697):eadk0582. doi: 10.1126/science.adk0582. Epub 2024 May 17. Science. 2024. PMID: 38753770
Brief Report: Impact of Anti-Cancer Treatments on Outcomes of COVID-19 in Patients With Thoracic Cancers: A CCC19 Registry Analysis.
Kulkarni AA, Hennessy C, Wilson G, Ramesh V, Hwang C, Awosika J, Bakouny Z, Khan H, Vilar-Compte D, McKay R, Jani C, Weissmann L, Griffiths E, Batist G, Bouganim N, Mavromatis B, Bashir B, Nguyen RH, Riess JW, Puc M, Kasi A, Berg S, Castillo DR, Hayes-Lattin B, Hosmer W, Flora D, Mishra S, French B, Warner JL, Lopes G, Peters S, Florez N. Kulkarni AA, et al. Among authors: warner jl. Clin Lung Cancer. 2024 Apr 10:S1525-7304(24)00044-5. doi: 10.1016/j.cllc.2024.04.003. Online ahead of print. Clin Lung Cancer. 2024. PMID: 38744613 No abstract available.
2,615 results