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Amyloid Cardiomyopathy: Disease on the Rise.
Liao R, Ward JE. Liao R, et al. Among authors: ward je. Circ Res. 2017 Jun 9;120(12):1865-1867. doi: 10.1161/CIRCRESAHA.117.310643. Circ Res. 2017. PMID: 28596171 Free PMC article. Review. No abstract available.
Zebrafish model of amyloid light chain cardiotoxicity: regeneration versus degeneration.
Mishra S, Joshi S, Ward JE, Buys EP, Mishra D, Mishra D, Morgado I, Fisch S, Lavatelli F, Merlini G, Dorbala S, MacRae CA, Liao R. Mishra S, et al. Among authors: ward je. Am J Physiol Heart Circ Physiol. 2019 May 1;316(5):H1158-H1166. doi: 10.1152/ajpheart.00788.2018. Epub 2019 Mar 15. Am J Physiol Heart Circ Physiol. 2019. PMID: 30875258 Free PMC article.
Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway.
Shi J, Guan J, Jiang B, Brenner DA, Del Monte F, Ward JE, Connors LH, Sawyer DB, Semigran MJ, Macgillivray TE, Seldin DC, Falk R, Liao R. Shi J, et al. Among authors: ward je. Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4188-93. doi: 10.1073/pnas.0912263107. Epub 2010 Feb 11. Proc Natl Acad Sci U S A. 2010. PMID: 20150510 Free PMC article.
Association of acquired von Willebrand syndrome with AL amyloidosis.
Kos CA, Ward JE, Malek K, Sanchorawala V, Wright DG, O'Hara C, Connors L, Skinner M, Seldin DC. Kos CA, et al. Among authors: ward je. Am J Hematol. 2007 May;82(5):363-7. doi: 10.1002/ajh.20829. Am J Hematol. 2007. PMID: 17205535 Free article.
Preclinical development of siRNA therapeutics for AL amyloidosis.
Hovey BM, Ward JE, Soo Hoo P, O'Hara CJ, Connors LH, Seldin DC. Hovey BM, et al. Among authors: ward je. Gene Ther. 2011 Dec;18(12):1150-6. doi: 10.1038/gt.2011.69. Epub 2011 May 12. Gene Ther. 2011. PMID: 21562591 Free PMC article.
Selective MCL-1 inhibitor ABBV-467 is efficacious in tumor models but is associated with cardiac troponin increases in patients.
Yuda J, Will C, Phillips DC, Abraham L, Alvey C, Avigdor A, Buck W, Besenhofer L, Boghaert E, Cheng D, Cojocari D, Doyle K, Hansen TM, Huang K, Johnson EF, Judd AS, Judge RA, Kalvass JC, Kunzer A, Lam LT, Li R, Martin RL, Mastracchio A, Mitten M, Petrich A, Wang J, Ward JE, Zhang H, Wang X, Wolff JE, Bell-McGuinn KM, Souers AJ. Yuda J, et al. Among authors: ward je. Commun Med (Lond). 2023 Oct 25;3(1):154. doi: 10.1038/s43856-023-00380-z. Commun Med (Lond). 2023. PMID: 37880389 Free PMC article.
249 results