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Progerin modulates the IGF-1R/Akt signaling involved in aging.
Jiang B, Wu X, Meng F, Si L, Cao S, Dong Y, Sun H, Lv M, Xu H, Bai N, Guo Q, Song X, Yu Y, Guo W, Yi F, Zhou T, Li X, Feng Y, Wang Z, Zhang D, Guan Y, Ma M, Liu J, Li X, Zhao W, Liu B, Finkel T, Cao L. Jiang B, et al. Among authors: wang z. Sci Adv. 2022 Jul 8;8(27):eabo0322. doi: 10.1126/sciadv.abo0322. Epub 2022 Jul 8. Sci Adv. 2022. PMID: 35857466 Free PMC article.
Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice.
Bai N, Li N, Cheng R, Guan Y, Zhao X, Song Z, Xu H, Yi F, Jiang B, Li X, Wu X, Jiang C, Zhou T, Guo Q, Guo W, Feng Y, Wang Z, Ma M, Yu Y, Wang Z, Zhang S, Wang C, Zhao W, Liu S, Song X, Liu H, Cao L. Bai N, et al. Among authors: wang z, wang c. Cell Rep. 2022 Jul 12;40(2):111062. doi: 10.1016/j.celrep.2022.111062. Cell Rep. 2022. PMID: 35830807 Free article.
The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis.
Yi F, Zhang Y, Wang Z, Wang Z, Li Z, Zhou T, Xu H, Liu J, Jiang B, Li X, Wang L, Bai N, Guo Q, Guan Y, Feng Y, Mao Z, Fan G, Zhang S, Wang C, Cao L, O'Rourke BP, Wang Y, Wu Y, Wu B, You S, Zhang N, Guan J, Song X, Sun Y, Wei S, Cao L. Yi F, et al. Among authors: wang l, wang z, wang y, wang c. Sci Adv. 2021 Feb 24;7(9):eabe5518. doi: 10.1126/sciadv.abe5518. Print 2021 Feb. Sci Adv. 2021. PMID: 33627431 Free PMC article.
ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.
Guo QQ, Wang SS, Zhang SS, Xu HD, Li XM, Guan Y, Yi F, Zhou TT, Jiang B, Bai N, Ma MT, Wang Z, Feng YL, Guo WD, Wu X, Zhao GF, Fan GJ, Zhang SP, Wang CG, Cao LY, O'Rourke BP, Liu SH, Wang PY, Han S, Song XY, Cao L. Guo QQ, et al. Among authors: wang ss, wang z, wang cg, wang py. EMBO J. 2020 May 18;39(10):e103111. doi: 10.15252/embj.2019103111. Epub 2020 Mar 18. EMBO J. 2020. PMID: 32187724 Free PMC article.
RNF8 induces β-catenin-mediated c-Myc expression and promotes colon cancer proliferation.
Ren L, Zhou T, Wang Y, Wu Y, Xu H, Liu J, Dong X, Yi F, Guo Q, Wang Z, Li X, Bai N, Guo W, Guo M, Jiang B, Wu X, Feng Y, Song X, Zhang S, Zhao Y, Cao L, Han S, Xing C. Ren L, et al. Among authors: wang z, wang y. Int J Biol Sci. 2020 May 1;16(12):2051-2062. doi: 10.7150/ijbs.44119. eCollection 2020. Int J Biol Sci. 2020. PMID: 32549753 Free PMC article.
The deacetylation of Foxk2 by Sirt1 reduces chemosensitivity to cisplatin.
Wang XW, Guo QQ, Yu Y, Zhou TT, Zhang SY, Wang Z, Liu JW, Tang J, Jiang XY, Wang SS, Guo WD, Xu HD, Sun HY, Li ZW, Song XY, Zhao JG, Cao L. Wang XW, et al. Among authors: wang ss, wang z. J Cell Mol Med. 2022 Jan;26(2):491-506. doi: 10.1111/jcmm.17107. Epub 2021 Dec 6. J Cell Mol Med. 2022. PMID: 34866322 Free PMC article.
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