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Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia.
Morrow MR, Batchuluun B, Wu J, Ahmadi E, Leroux JM, Mohammadi-Shemirani P, Desjardins EM, Wang Z, Tsakiridis EE, Lavoie DCT, Reihani A, Smith BK, Kwiecien JM, Lally JSV, Nero TL, Parker MW, Ask K, Scott JW, Jiang L, Paré G, Pinkosky SL, Steinberg GR. Morrow MR, et al. Among authors: wang z. Cell Metab. 2022 Jun 7;34(6):919-936.e8. doi: 10.1016/j.cmet.2022.05.004. Cell Metab. 2022. PMID: 35675800 Free article.
Metabolic reprogramming in the OPA1-deficient cells.
Dai W, Wang Z, Wang QA, Chan D, Jiang L. Dai W, et al. Among authors: wang qa, wang z. Cell Mol Life Sci. 2022 Sep 14;79(10):517. doi: 10.1007/s00018-022-04542-5. Cell Mol Life Sci. 2022. PMID: 36103091
Energy metabolism in brown adipose tissue.
Wang Z, Wang QA, Liu Y, Jiang L. Wang Z, et al. Among authors: wang qa. FEBS J. 2021 Jun;288(12):3647-3662. doi: 10.1111/febs.16015. Epub 2021 May 24. FEBS J. 2021. PMID: 34028971 Free article. Review.
Metabolic convergence on lipogenesis in RAS, BCR-ABL, and MYC-driven lymphoid malignancies.
Liefwalker DF, Ryan M, Wang Z, Pathak KV, Plaisier S, Shah V, Babra B, Dewson GS, Lai IK, Mosley AR, Fueger PT, Casey SC, Jiang L, Pirrotte P, Swaminathan S, Sears RC. Liefwalker DF, et al. Among authors: wang z. Cancer Metab. 2021 Aug 16;9(1):31. doi: 10.1186/s40170-021-00263-8. Cancer Metab. 2021. PMID: 34399819 Free PMC article.
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1.
Li M, Zhang CS, Feng JW, Wei X, Zhang C, Xie C, Wu Y, Hawley SA, Atrih A, Lamont DJ, Wang Z, Piao HL, Hardie DG, Lin SC. Li M, et al. Among authors: wang z. Cell Res. 2021 Apr;31(4):478-481. doi: 10.1038/s41422-020-00456-8. Epub 2020 Dec 21. Cell Res. 2021. PMID: 33349646 Free PMC article. No abstract available.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC. Zhang CS, et al. Among authors: wang w, wang zx, wang y, wang zc. Nat Metab. 2022 Oct;4(10):1369-1401. doi: 10.1038/s42255-022-00640-7. Epub 2022 Oct 10. Nat Metab. 2022. PMID: 36217034 Free PMC article.
126,309 results
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