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The deubiquitylase USP2 maintains ErbB2 abundance via counteracting endocytic degradation and represents a therapeutic target in ErbB2-positive breast cancer.
Zhang J, Liu S, Li Q, Shi Y, Wu Y, Liu F, Wang S, Zaky MY, Yousuf W, Sun Q, Guo D, Wang T, Zhang Y, Wang Y, Li M, Liu H. Zhang J, et al. Among authors: wang y, wang t, wang s. Cell Death Differ. 2020 Sep;27(9):2710-2725. doi: 10.1038/s41418-020-0538-8. Epub 2020 Apr 23. Cell Death Differ. 2020. PMID: 32327714 Free PMC article.
E3 ubiquitin ligases: styles, structures and functions.
Yang Q, Zhao J, Chen D, Wang Y. Yang Q, et al. Among authors: wang y. Mol Biomed. 2021 Jul 30;2(1):23. doi: 10.1186/s43556-021-00043-2. Mol Biomed. 2021. PMID: 35006464 Free PMC article. Review.
Nuclear Aurora kinase A switches m6A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4.
Li S, Qi Y, Yu J, Hao Y, He B, Zhang M, Dai Z, Jiang T, Li S, Huang F, Chen N, Wang J, Yang M, Liang D, An F, Zhao J, Fan W, Pan Y, Deng Z, Luo Y, Guo T, Peng F, Hou Z, Wang C, Zheng F, Xu L, Xu J, Wen Q, Jin B, Wang Y, Liu Q. Li S, et al. Among authors: wang j, wang y, wang c. Signal Transduct Target Ther. 2022 Apr 1;7(1):97. doi: 10.1038/s41392-022-00905-3. Signal Transduct Target Ther. 2022. PMID: 35361747 Free PMC article.
Loss of RBMS1 promotes anti-tumor immunity through enabling PD-L1 checkpoint blockade in triple-negative breast cancer.
Zhang J, Zhang G, Zhang W, Bai L, Wang L, Li T, Yan L, Xu Y, Chen D, Gao W, Gao C, Chen C, Ren M, Jiao Y, Qin H, Sun Y, Zhi L, Qi Y, Zhao J, Liu Q, Liu H, Wang Y. Zhang J, et al. Among authors: wang l, wang y. Cell Death Differ. 2022 Nov;29(11):2247-2261. doi: 10.1038/s41418-022-01012-0. Epub 2022 May 10. Cell Death Differ. 2022. PMID: 35538152 Free PMC article.
A widespread length-dependent splicing dysregulation in cancer.
Zhang S, Mao M, Lv Y, Yang Y, He W, Song Y, Wang Y, Yang Y, Al Abo M, Freedman JA, Patierno SR, Wang Y, Wang Z. Zhang S, et al. Among authors: wang z, wang y. Sci Adv. 2022 Aug 19;8(33):eabn9232. doi: 10.1126/sciadv.abn9232. Epub 2022 Aug 17. Sci Adv. 2022. PMID: 35977015 Free PMC article.
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