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Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.
Mitchell CA, Verovskaya EV, Calero-Nieto FJ, Olson OC, Swann JW, Wang X, Hérault A, Dellorusso PV, Zhang SY, Svendsen AF, Pietras EM, Bakker ST, Ho TT, Göttgens B, Passegué E. Mitchell CA, et al. Among authors: wang x. Nat Cell Biol. 2023 Jan;25(1):30-41. doi: 10.1038/s41556-022-01053-0. Epub 2023 Jan 17. Nat Cell Biol. 2023. PMID: 36650381 Free PMC article.
Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.
Tijssen MR, Cvejic A, Joshi A, Hannah RL, Ferreira R, Forrai A, Bellissimo DC, Oram SH, Smethurst PA, Wilson NK, Wang X, Ottersbach K, Stemple DL, Green AR, Ouwehand WH, Göttgens B. Tijssen MR, et al. Among authors: wang x. Dev Cell. 2011 May 17;20(5):597-609. doi: 10.1016/j.devcel.2011.04.008. Dev Cell. 2011. PMID: 21571218 Free PMC article.
Three distinct patterns of histone H3Y41 phosphorylation mark active genes.
Dawson MA, Foster SD, Bannister AJ, Robson SC, Hannah R, Wang X, Xhemalce B, Wood AD, Green AR, Göttgens B, Kouzarides T. Dawson MA, et al. Among authors: wang x. Cell Rep. 2012 Sep 27;2(3):470-7. doi: 10.1016/j.celrep.2012.08.016. Epub 2012 Sep 20. Cell Rep. 2012. PMID: 22999934 Free PMC article.
Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.
Hérault A, Binnewies M, Leong S, Calero-Nieto FJ, Zhang SY, Kang YA, Wang X, Pietras EM, Chu SH, Barry-Holson K, Armstrong S, Göttgens B, Passegué E. Hérault A, et al. Among authors: wang x. Nature. 2017 Apr 6;544(7648):53-58. doi: 10.1038/nature21693. Epub 2017 Mar 29. Nature. 2017. PMID: 28355185 Free PMC article.
Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq.
Lescroart F, Wang X, Lin X, Swedlund B, Gargouri S, Sànchez-Dànes A, Moignard V, Dubois C, Paulissen C, Kinston S, Göttgens B, Blanpain C. Lescroart F, et al. Among authors: wang x. Science. 2018 Mar 9;359(6380):1177-1181. doi: 10.1126/science.aao4174. Epub 2018 Jan 25. Science. 2018. PMID: 29371425 Free PMC article.
Enhanced hemato-endothelial specification during human embryonic differentiation through developmental cooperation between AF4-MLL and MLL-AF4 fusions.
Bueno C, Calero-Nieto FJ, Wang X, Valdés-Mas R, Gutiérrez-Agüera F, Roca-Ho H, Ayllon V, Real PJ, Arambilet D, Espinosa L, Torres-Ruiz R, Agraz-Doblas A, Varela I, de Boer J, Bigas A, Gottgens B, Marschalek R, Menendez P. Bueno C, et al. Among authors: wang x. Haematologica. 2019 Jun;104(6):1189-1201. doi: 10.3324/haematol.2018.202044. Epub 2019 Jan 24. Haematologica. 2019. PMID: 30679325 Free PMC article.
GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm.
Castaño J, Aranda S, Bueno C, Calero-Nieto FJ, Mejia-Ramirez E, Mosquera JL, Blanco E, Wang X, Prieto C, Zabaleta L, Mereu E, Rovira M, Jiménez-Delgado S, Matson DR, Heyn H, Bresnick EH, Göttgens B, Di Croce L, Menendez P, Raya A, Giorgetti A. Castaño J, et al. Among authors: wang x. Stem Cell Reports. 2019 Sep 10;13(3):515-529. doi: 10.1016/j.stemcr.2019.07.009. Epub 2019 Aug 8. Stem Cell Reports. 2019. PMID: 31402335 Free PMC article.
Notch ligand Dll4 impairs cell recruitment to aortic clusters and limits blood stem cell generation.
Porcheri C, Golan O, Calero-Nieto FJ, Thambyrajah R, Ruiz-Herguido C, Wang X, Catto F, Guillén Y, Sinha R, González J, Kinston SJ, Mariani SA, Maglitto A, Vink CS, Dzierzak E, Charbord P, Göttgens B, Espinosa L, Sprinzak D, Bigas A. Porcheri C, et al. Among authors: wang x. EMBO J. 2020 Apr 15;39(8):e104270. doi: 10.15252/embj.2019104270. Epub 2020 Mar 9. EMBO J. 2020. PMID: 32149421 Free PMC article.
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