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Circular RNA circ-TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA.
Pan X, Huang B, Ma Q, Ren J, Liu Y, Wang C, Zhang D, Fu J, Ran L, Yu T, Li H, Wang X, Yang F, Liang C, Zhang Y, Wang S, Ren J, Li W, Wang Y, Xiao B. Pan X, et al. Among authors: wang x, wang y, wang c, wang s. Clin Transl Med. 2022 Jul;12(7):e994. doi: 10.1002/ctm2.994. Clin Transl Med. 2022. PMID: 35876041 Free PMC article.
Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL.
Yu T, Ran L, Zhao H, Yin P, Li W, Lin J, Mao H, Cai D, Ma Q, Pan X, Wang X, Wu J, Zeng H, Zhang W, Lu D, Luo P, Zou Q, Xiao B. Yu T, et al. Among authors: wang x. Mol Ther Nucleic Acids. 2021 Aug 28;26:649-664. doi: 10.1016/j.omtn.2021.08.029. eCollection 2021 Dec 3. Mol Ther Nucleic Acids. 2021. PMID: 34703650 Free PMC article.
CircARID1A binds to IGF2BP3 in gastric cancer and promotes cancer proliferation by forming a circARID1A-IGF2BP3-SLC7A5 RNA-protein ternary complex.
Ma Q, Yang F, Huang B, Pan X, Li W, Yu T, Wang X, Ran L, Qian K, Li H, Li H, Liu Y, Liang C, Ren J, Zhang Y, Wang S, Xiao B. Ma Q, et al. Among authors: wang x, wang s. J Exp Clin Cancer Res. 2022 Aug 19;41(1):251. doi: 10.1186/s13046-022-02466-3. J Exp Clin Cancer Res. 2022. PMID: 35986300 Free PMC article.
Exportin 4 depletion leads to nuclear accumulation of a subset of circular RNAs.
Chen L, Wang Y, Lin J, Song Z, Wang Q, Zhao W, Wang Y, Xiu X, Deng Y, Li X, Li Q, Wang X, Li J, Liu X, Liu K, Zhou J, Li K, Liu Y, Liao S, Deng Q, Xu C, Sun Q, Wu S, Zhang K, Guan MX, Zhou T, Sun F, Cai X, Huang C, Shan G. Chen L, et al. Among authors: wang x, wang y, wang q. Nat Commun. 2022 Oct 1;13(1):5769. doi: 10.1038/s41467-022-33356-z. Nat Commun. 2022. PMID: 36182935 Free PMC article.
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