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Development of ProTx-II Analogues as Highly Selective Peptide Blockers of Nav1.7 for the Treatment of Pain.
Adams GL, Pall PS, Grauer SM, Zhou X, Ballard JE, Vavrek M, Kraus RL, Morissette P, Li N, Colarusso S, Bianchi E, Palani A, Klein R, John CT, Wang D, Tudor M, Nolting AF, Biba M, Nowak T, Makarov AA, Reibarkh M, Buevich AV, Zhong W, Regalado EL, Wang X, Gao Q, Shahripour A, Zhu Y, de Simone D, Frattarelli T, Pasquini NM, Magotti P, Iaccarino R, Li Y, Solly K, Lee KJ, Wang W, Chen F, Zeng H, Wang J, Regan H, Amin RP, Regan CP, Burgey CS, Henze DA, Sun C, Tellers DM. Adams GL, et al. Among authors: wang x, wang w, wang j, wang d. J Med Chem. 2022 Jan 13;65(1):485-496. doi: 10.1021/acs.jmedchem.1c01570. Epub 2021 Dec 21. J Med Chem. 2022. PMID: 34931831
Unexpected Propargylic Retro-Brook Rearrangements in Alkynes.
Wang X, Gao Q, Buevich AV, Yasuda N, Zhang Y, Yang RS, Zhang LK, Martin GE, Williamson RT. Wang X, et al. J Org Chem. 2019 Aug 16;84(16):10024-10031. doi: 10.1021/acs.joc.9b01190. Epub 2019 Jul 22. J Org Chem. 2019. PMID: 31283876
Denigrins and Dactylpyrroles, Arylpyrrole Alkaloids from a Dactylia sp. Marine Sponge.
Kang U, Cartner LK, Wang D, Kim CK, Thomas CL, Woldemichael GM, Gryder BE, Shern JF, Khan J, Castello-Branco C, Sherer EC, Wang X, Regalado EL, Gustafson KR. Kang U, et al. Among authors: wang x, wang d. J Nat Prod. 2020 Nov 25;83(11):3464-3470. doi: 10.1021/acs.jnatprod.0c01103. Epub 2020 Nov 5. J Nat Prod. 2020. PMID: 33151696 Free PMC article.
Discovery of MK-4688: an Efficient Inhibitor of the HDM2-p53 Protein-Protein Interaction.
Reutershan MH, Machacek MR, Altman MD, Bogen S, Cai M, Cammarano C, Chen D, Christopher M, Cryan J, Daublain P, Fradera X, Geda P, Goldenblatt P, Hill AD, Kemper RA, Kutilek V, Li C, Martinez M, McCoy M, Nair L, Pan W, Thompson CF, Scapin G, Shizuka M, Spatz ML, Steinhuebel D, Sun B, Voss ME, Wang X, Yang L, Yeh TC, Dussault I, Marshall CG, Trotter BW. Reutershan MH, et al. Among authors: wang x. J Med Chem. 2021 Nov 11;64(21):16213-16241. doi: 10.1021/acs.jmedchem.1c01524. Epub 2021 Oct 29. J Med Chem. 2021. PMID: 34714078
Trapping-Enrichment Multi-dimensional Liquid Chromatography with On-Line Deuterated Solvent Exchange for Streamlined Structure Elucidation at the Microgram Scale.
Ahmad IAH, Losacco GL, Shchurik V, Wang X, Cohen RD, Herron AN, Aiken S, Fiorito D, Wang H, Reibarkh M, Nowak T, Makarov AA, Stoll DR, Guillarme D, Mangion I, Aggarwal VK, Yu JQ, Regalado EL. Ahmad IAH, et al. Among authors: wang x, wang h. Angew Chem Int Ed Engl. 2022 May 16;61(21):e202117655. doi: 10.1002/anie.202117655. Epub 2022 Feb 21. Angew Chem Int Ed Engl. 2022. PMID: 35139257
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