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Probing the dynamic stalk region of the ribosome using solution NMR.
Wang X, Kirkpatrick JP, Launay HMM, de Simone A, Häussinger D, Dobson CM, Vendruscolo M, Cabrita LD, Waudby CA, Christodoulou J. Wang X, et al. Sci Rep. 2019 Sep 19;9(1):13528. doi: 10.1038/s41598-019-49190-1. Sci Rep. 2019. PMID: 31537834 Free PMC article.
A structural ensemble of a ribosome-nascent chain complex during cotranslational protein folding.
Cabrita LD, Cassaignau AME, Launay HMM, Waudby CA, Wlodarski T, Camilloni C, Karyadi ME, Robertson AL, Wang X, Wentink AS, Goodsell L, Woolhead CA, Vendruscolo M, Dobson CM, Christodoulou J. Cabrita LD, et al. Among authors: wang x. Nat Struct Mol Biol. 2016 Apr;23(4):278-285. doi: 10.1038/nsmb.3182. Epub 2016 Feb 29. Nat Struct Mol Biol. 2016. PMID: 26926436 Free PMC article.
Common sequence motifs of nascent chains engage the ribosome surface and trigger factor.
Deckert A, Cassaignau AME, Wang X, Włodarski T, Chan SHS, Waudby CA, Kirkpatrick JP, Vendruscolo M, Cabrita LD, Christodoulou J. Deckert A, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2021 Dec 28;118(52):e2103015118. doi: 10.1073/pnas.2103015118. Proc Natl Acad Sci U S A. 2021. PMID: 34930833 Free PMC article.
Structural characterization of the interaction of α-synuclein nascent chains with the ribosomal surface and trigger factor.
Deckert A, Waudby CA, Wlodarski T, Wentink AS, Wang X, Kirkpatrick JP, Paton JF, Camilloni C, Kukic P, Dobson CM, Vendruscolo M, Cabrita LD, Christodoulou J. Deckert A, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2016 May 3;113(18):5012-7. doi: 10.1073/pnas.1519124113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27092002 Free PMC article.
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