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Drug Discovery Targeting Anaplastic Lymphoma Kinase (ALK).
Kong X, Pan P, Sun H, Xia H, Wang X, Li Y, Hou T. Kong X, et al. Among authors: wang x. J Med Chem. 2019 Dec 26;62(24):10927-10954. doi: 10.1021/acs.jmedchem.9b00446. Epub 2019 Aug 26. J Med Chem. 2019. PMID: 31419130 Review.
Structure-Based Drug Design and Identification of H2O-Soluble and Low Toxic Hexacyclic Camptothecin Derivatives with Improved Efficacy in Cancer and Lethal Inflammation Models in Vivo.
Pan P, Chen J, Li X, Li M, Yu H, Zhao JJ, Ni J, Wang X, Sun H, Tian S, Zhu F, Liu F, Huang Y, Hou T. Pan P, et al. Among authors: wang x. J Med Chem. 2018 Oct 11;61(19):8613-8624. doi: 10.1021/acs.jmedchem.8b00498. Epub 2018 Sep 27. J Med Chem. 2018. PMID: 30227711 Free PMC article.
Discovery of a Novel Androgen Receptor Antagonist Manifesting Evidence to Disrupt the Dimerization of the Ligand-Binding Domain via Attenuating the Hydrogen-Bonding Network Between the Two Monomers.
Fu W, Zhang M, Liao J, Tang Q, Lei Y, Gong Z, Shan L, Duan M, Chai X, Pang J, Tang C, Wang X, Xu X, Li D, Sheng R, Hou T. Fu W, et al. Among authors: wang x. J Med Chem. 2021 Dec 9;64(23):17221-17238. doi: 10.1021/acs.jmedchem.1c01287. Epub 2021 Nov 22. J Med Chem. 2021. PMID: 34809430
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