Wang S - Search Results

1

Recognition of methamphetamine and other amines by trace amine receptor TAAR1.

Liu H, Zheng Y, Wang Y, Wang Y, He X, Xu P, Huang S, Yuan Q, Zhang X, Wang L, Jiang K, Chen H, Li Z, Liu W, Wang S, Xu HE, Xu F. Liu H, et al. Among authors: wang l, wang y, wang s. Nature. 2023 Dec;624(7992):663-671. doi: 10.1038/s41586-023-06775-1. Epub 2023 Nov 7. Nature. 2023. PMID: 37935377

2

Haloperidol bound D₂ dopamine receptor structure inspired the discovery of subtype selective ligands.

Fan L, Tan L, Chen Z, Qi J, Nie F, Luo Z, Cheng J, Wang S. Fan L, et al. Among authors: wang s. Nat Commun. 2020 Feb 26;11(1):1074. doi: 10.1038/s41467-020-14884-y. Nat Commun. 2020. PMID: 32103023 Free PMC article.

3

Crystal structure of steroid reductase SRD5A reveals conserved steroid reduction mechanism.

Han Y, Zhuang Q, Sun B, Lv W, Wang S, Xiao Q, Pang B, Zhou Y, Wang F, Chi P, Wang Q, Li Z, Zhu L, Li F, Deng D, Chiang YC, Li Z, Ren R. Han Y, et al. Among authors: wang f, wang s, wang q. Nat Commun. 2021 Jan 19;12(1):449. doi: 10.1038/s41467-020-20675-2. Nat Commun. 2021. PMID: 33469028 Free PMC article.

4

Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties.

Chen Z, Fan L, Wang H, Yu J, Lu D, Qi J, Nie F, Luo Z, Liu Z, Cheng J, Wang S. Chen Z, et al. Among authors: wang h, wang s. Nat Neurosci. 2022 Jan;25(1):39-49. doi: 10.1038/s41593-021-00971-w. Epub 2021 Dec 9. Nat Neurosci. 2022. PMID: 34887590

5

The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands.

Wang J, Wu M, Chen Z, Wu L, Wang T, Cao D, Wang H, Liu S, Xu Y, Li F, Liu J, Chen N, Zhao S, Cheng J, Wang S, Hua T. Wang J, et al. Among authors: wang h, wang t, wang s. Nat Commun. 2022 May 23;13(1):2855. doi: 10.1038/s41467-022-30595-y. Nat Commun. 2022. PMID: 35606397 Free PMC article.

6

Flexible scaffold-based cheminformatics approach for polypharmacological drug design.

Chen Z, Yu J, Wang H, Xu P, Fan L, Sun F, Huang S, Zhang P, Huang H, Gu S, Zhang B, Zhou Y, Wan X, Pei G, Xu HE, Cheng J, Wang S. Chen Z, et al. Among authors: wang h, wang s. Cell. 2024 Apr 25;187(9):2194-2208.e22. doi: 10.1016/j.cell.2024.02.034. Epub 2024 Mar 28. Cell. 2024. PMID: 38552625

7

Structure of the D2 dopamine receptor bound to the atypical antipsychotic drug risperidone.

Wang S, Che T, Levit A, Shoichet BK, Wacker D, Roth BL. Wang S, et al. Nature. 2018 Mar 8;555(7695):269-273. doi: 10.1038/nature25758. Epub 2018 Jan 24. Nature. 2018. PMID: 29466326 Free PMC article.

8

Structural determinants of 5-HT_2B receptor activation and biased agonism.

McCorvy JD, Wacker D, Wang S, Agegnehu B, Liu J, Lansu K, Tribo AR, Olsen RHJ, Che T, Jin J, Roth BL. McCorvy JD, et al. Among authors: wang s. Nat Struct Mol Biol. 2018 Sep;25(9):787-796. doi: 10.1038/s41594-018-0116-7. Epub 2018 Aug 20. Nat Struct Mol Biol. 2018. PMID: 30127358 Free PMC article.

9

Ultra-large library docking for discovering new chemotypes.

Lyu J, Wang S, Balius TE, Singh I, Levit A, Moroz YS, O'Meara MJ, Che T, Algaa E, Tolmachova K, Tolmachev AA, Shoichet BK, Roth BL, Irwin JJ. Lyu J, et al. Among authors: wang s. Nature. 2019 Feb;566(7743):224-229. doi: 10.1038/s41586-019-0917-9. Epub 2019 Feb 6. Nature. 2019. PMID: 30728502 Free PMC article.

10

Nanobody-enabled monitoring of kappa opioid receptor states.

Che T, English J, Krumm BE, Kim K, Pardon E, Olsen RHJ, Wang S, Zhang S, Diberto JF, Sciaky N, Carroll FI, Steyaert J, Wacker D, Roth BL. Che T, et al. Among authors: wang s. Nat Commun. 2020 Mar 2;11(1):1145. doi: 10.1038/s41467-020-14889-7. Nat Commun. 2020. PMID: 32123179 Free PMC article.

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