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The Aging Biomarker Consortium represents a new era for aging research in China.
Ren J, Song M, Zhang W, Cai JP, Cao F, Cao Z, Chan P, Chen C, Chen G, Chen HZ, Chen J, Chen XC, Ci W, Ding BS, Ding Q, Gao F, Gao S, Han JJ, He QY, Huang K, Ju Z, Kong QP, Li J, Li J, Li J, Li X, Liu B, Liu F, Liu JP, Liu L, Liu Q, Liu Q, Liu X, Liu Y, Luo X, Ma S, Ma X, Mao Z, Nie J, Peng Y, Qu J, Ren R, Song W, Songyang Z, Sun L, Sun YE, Sun Y, Tian M, Tian XL, Tian Y, Wang J, Wang S, Wang S, Wang W, Wang X, Wang X, Wang YJ, Wang Y, Wong CCL, Xiang AP, Xiao Y, Xiao ZX, Xie Z, Xiong W, Xu D, Yang Z, Ye J, Yu W, Yue R, Zhang C, Zhang H, Zhang L, Zhang X, Zhang Y, Zhang YW, Zhang Z, Zhao T, Zhao Y, Zhou Z, Zhu D, Zou W, Pei G, Liu GH. Ren J, et al. Among authors: wang x, wang w, wang j, wang yj, wang y, wang s. Nat Med. 2023 Sep;29(9):2162-2165. doi: 10.1038/s41591-023-02444-y. Nat Med. 2023. PMID: 37468667 No abstract available.
Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates.
Du Y, Liang Z, Wang S, Sun D, Wang X, Liew SY, Lu S, Wu S, Jiang Y, Wang Y, Zhang B, Yu W, Lu Z, Pu Y, Zhang Y, Long H, Xiao S, Liang R, Zhang Z, Guan J, Wang J, Ren H, Wei Y, Zhao J, Sun S, Liu T, Meng G, Wang L, Gu J, Wang T, Liu Y, Li C, Tang C, Shen Z, Peng X, Deng H. Du Y, et al. Among authors: wang x, wang l, wang j, wang y, wang t, wang s. Nat Med. 2022 Feb;28(2):272-282. doi: 10.1038/s41591-021-01645-7. Epub 2022 Feb 3. Nat Med. 2022. PMID: 35115708
Implantation underneath the abdominal anterior rectus sheath enables effective and functional engraftment of stem-cell-derived islets.
Liang Z, Sun D, Lu S, Lei Z, Wang S, Luo Z, Zhan J, Wu S, Jiang Y, Lu Z, Sun S, Shi Y, Long H, Wei Y, Yu W, Wang Z, Yi LS, Zhang Y, Sun W, Fang X, Li Y, Lu S, Lv J, Sui W, Shen Z, Peng X, Du Y, Deng H. Liang Z, et al. Among authors: wang z, wang s. Nat Metab. 2023 Jan;5(1):29-40. doi: 10.1038/s42255-022-00713-7. Epub 2023 Jan 9. Nat Metab. 2023. PMID: 36624157
Galectin-3 impairs calcium transients and β-cell function.
Jiang Q, Zhao Q, Chen Y, Ma C, Peng X, Wu X, Liu X, Wang R, Hou S, Kong L, Wan Y, Wang S, Meng ZX, Cui B, Chen L, Li P. Jiang Q, et al. Among authors: wang s, wang r. Nat Commun. 2024 May 1;15(1):3682. doi: 10.1038/s41467-024-47959-1. Nat Commun. 2024. PMID: 38693121 Free PMC article.
IER3IP1 is critical for maintaining glucose homeostasis through regulating the endoplasmic reticulum function and survival of β cells.
Yang J, Zhen J, Feng W, Fan Z, Ding L, Yang X, Huang Y, Shu H, Xie J, Li X, Qiao J, Fan Y, Sun J, Li N, Liu T, Wang S, Zhang X, Arvan P, Liu M. Yang J, et al. Among authors: wang s. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2204443119. doi: 10.1073/pnas.2204443119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322741 Free PMC article.
Trimethylamine N-oxide impairs β-cell function and glucose tolerance.
Kong L, Zhao Q, Jiang X, Hu J, Jiang Q, Sheng L, Peng X, Wang S, Chen Y, Wan Y, Hou S, Liu X, Ma C, Li Y, Quan L, Chen L, Cui B, Li P. Kong L, et al. Among authors: wang s. Nat Commun. 2024 Mar 21;15(1):2526. doi: 10.1038/s41467-024-46829-0. Nat Commun. 2024. PMID: 38514666 Free PMC article.
BRSK2 in pancreatic β cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes.
Xu R, Wang K, Yao Z, Zhang Y, Jin L, Pang J, Zhou Y, Wang K, Liu D, Zhang Y, Sun P, Wang F, Chang X, Liu T, Wang S, Zhang Y, Lin S, Hu C, Zhu Y, Han X. Xu R, et al. Among authors: wang f, wang k, wang s. J Mol Cell Biol. 2023 Nov 27;15(5):mjad033. doi: 10.1093/jmcb/mjad033. J Mol Cell Biol. 2023. PMID: 37188647 Free PMC article.
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