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TREM2 drives microglia response to amyloid-β via SYK-dependent and -independent pathways.
Wang S, Sudan R, Peng V, Zhou Y, Du S, Yuede CM, Lei T, Hou J, Cai Z, Cella M, Nguyen K, Poliani PL, Beatty WL, Chen Y, Cao S, Lin K, Rodrigues C, Ellebedy AH, Gilfillan S, Brown GD, Holtzman DM, Brioschi S, Colonna M. Wang S, et al. Cell. 2022 Oct 27;185(22):4153-4169.e19. doi: 10.1016/j.cell.2022.09.033. Cell. 2022. PMID: 36306735 Free PMC article.
Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer's disease.
Ellwanger DC, Wang S, Brioschi S, Shao Z, Green L, Case R, Yoo D, Weishuhn D, Rathanaswami P, Bradley J, Rao S, Cha D, Luan P, Sambashivan S, Gilfillan S, Hasson SA, Foltz IN, van Lookeren Campagne M, Colonna M. Ellwanger DC, et al. Among authors: wang s. Proc Natl Acad Sci U S A. 2021 Jan 19;118(3):e2017742118. doi: 10.1073/pnas.2017742118. Proc Natl Acad Sci U S A. 2021. PMID: 33446504 Free PMC article.
A Cre-deleter specific for embryo-derived brain macrophages reveals distinct features of microglia and border macrophages.
Brioschi S, Belk JA, Peng V, Molgora M, Rodrigues PF, Nguyen KM, Wang S, Du S, Wang WL, Grajales-Reyes GE, Ponce JM, Yuede CM, Li Q, Baer JM, DeNardo DG, Gilfillan S, Cella M, Satpathy AT, Colonna M. Brioschi S, et al. Among authors: wang wl, wang s. Immunity. 2023 May 9;56(5):1027-1045.e8. doi: 10.1016/j.immuni.2023.01.028. Epub 2023 Feb 14. Immunity. 2023. PMID: 36791722 Free PMC article.
Antibody-mediated targeting of human microglial leukocyte Ig-like receptor B4 attenuates amyloid pathology in a mouse model.
Hou J, Chen Y, Cai Z, Heo GS, Yuede CM, Wang Z, Lin K, Saadi F, Trsan T, Nguyen AT, Constantopoulos E, Larsen RA, Zhu Y, Wagner ND, McLaughlin N, Kuang XC, Barrow AD, Li D, Zhou Y, Wang S, Gilfillan S, Gross ML, Brioschi S, Liu Y, Holtzman DM, Colonna M. Hou J, et al. Among authors: wang z, wang s. Sci Transl Med. 2024 Apr 3;16(741):eadj9052. doi: 10.1126/scitranslmed.adj9052. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569016
Lyl-1 regulates primitive macrophages and microglia development.
Wang S, Ren D, Arkoun B, Kaushik AL, Matherat G, Lécluse Y, Filipp D, Vainchenker W, Raslova H, Plo I, Godin I. Wang S, et al. Commun Biol. 2021 Dec 9;4(1):1382. doi: 10.1038/s42003-021-02886-5. Commun Biol. 2021. PMID: 34887504 Free PMC article.
109,388 results
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