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Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages.
Marcotte H, Cao Y, Zuo F, Simonelli L, Sammartino JC, Pedotti M, Sun R, Cassaniti I, Hagbom M, Piralla A, Yang J, Du L, Percivalle E, Bertoglio F, Schubert M, Abolhassani H, Sherina N, Guerra C, Borte S, Rezaei N, Kumagai-Braesch M, Xue Y, Su C, Yan Q, He P, Grönwall C, Klareskog L, Calzolai L, Cavalli A, Wang Q, Robbiani DF, Hust M, Shi Z, Feng L, Svensson L, Chen L, Bao L, Baldanti F, Xiao J, Qin C, Hammarström L, Yang X, Varani L, Xie XS, Pan-Hammarström Q. Marcotte H, et al. Among authors: wang q. Proc Natl Acad Sci U S A. 2024 Jan 16;121(3):e2315354120. doi: 10.1073/pnas.2315354120. Epub 2024 Jan 9. Proc Natl Acad Sci U S A. 2024. PMID: 38194459 Free PMC article.
Epigenetic targeting of activation-induced cytidine deaminase.
Wang Q, Oliveira T, Jankovic M, Silva IT, Hakim O, Yao K, Gazumyan A, Mayer CT, Pavri R, Casellas R, Nussenzweig MC, Robbiani DF. Wang Q, et al. Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18667-72. doi: 10.1073/pnas.1420575111. Epub 2014 Dec 15. Proc Natl Acad Sci U S A. 2014. PMID: 25512519 Free PMC article.
A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates.
Keeffe JR, Van Rompay KKA, Olsen PC, Wang Q, Gazumyan A, Azzopardi SA, Schaefer-Babajew D, Lee YE, Stuart JB, Singapuri A, Watanabe J, Usachenko J, Ardeshir A, Saeed M, Agudelo M, Eisenreich T, Bournazos S, Oliveira TY, Rice CM, Coffey LL, MacDonald MR, Bjorkman PJ, Nussenzweig MC, Robbiani DF. Keeffe JR, et al. Among authors: wang q. Cell Rep. 2018 Nov 6;25(6):1385-1394.e7. doi: 10.1016/j.celrep.2018.10.031. Cell Rep. 2018. PMID: 30403995 Free PMC article.
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques.
Van Rompay KKA, Coffey LL, Kapoor T, Gazumyan A, Keesler RI, Jurado A, Peace A, Agudelo M, Watanabe J, Usachenko J, Singapuri A, Immareddy R, Ardeshir A, Stuart JB, Bournazos S, Ravetch JV, Balderes PJ, Lorenz IC, Esswein SR, Keeffe JR, Bjorkman PJ, Wang Q, Rice CM, MacDonald MR, Nussenzweig MC, Robbiani DF. Van Rompay KKA, et al. Among authors: wang q. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):7981-7989. doi: 10.1073/pnas.2000414117. Epub 2020 Mar 24. Proc Natl Acad Sci U S A. 2020. PMID: 32209664 Free PMC article.
A Combination of Human Broadly Neutralizing Antibodies against Hepatitis B Virus HBsAg with Distinct Epitopes Suppresses Escape Mutations.
Wang Q, Michailidis E, Yu Y, Wang Z, Hurley AM, Oren DA, Mayer CT, Gazumyan A, Liu Z, Zhou Y, Schoofs T, Yao KH, Nieke JP, Wu J, Jiang Q, Zou C, Kabbani M, Quirk C, Oliveira T, Chhosphel K, Zhang Q, Schneider WM, Jahan C, Ying T, Horowitz J, Caskey M, Jankovic M, Robbiani DF, Wen Y, de Jong YP, Rice CM, Nussenzweig MC. Wang Q, et al. Among authors: wang z. Cell Host Microbe. 2020 Aug 12;28(2):335-349.e6. doi: 10.1016/j.chom.2020.05.010. Epub 2020 Jun 5. Cell Host Microbe. 2020. PMID: 32504577 Free PMC article.
Selection and structural bases of potent broadly neutralizing antibodies from 3-dose vaccinees that are highly effective against diverse SARS-CoV-2 variants, including Omicron sublineages.
Wang L, Fu W, Bao L, Jia Z, Zhang Y, Zhou Y, Wu W, Wu J, Zhang Q, Gao Y, Wang K, Wang Q, Qin C, Wang X. Wang L, et al. Among authors: wang x, wang k, wang q. Cell Res. 2022 Jul;32(7):691-694. doi: 10.1038/s41422-022-00677-z. Epub 2022 Jun 7. Cell Res. 2022. PMID: 35672388 Free PMC article. No abstract available.
Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.
Robbiani DF, Deroubaix S, Feldhahn N, Oliveira TY, Callen E, Wang Q, Jankovic M, Silva IT, Rommel PC, Bosque D, Eisenreich T, Nussenzweig A, Nussenzweig MC. Robbiani DF, et al. Among authors: wang q. Cell. 2015 Aug 13;162(4):727-37. doi: 10.1016/j.cell.2015.07.019. Cell. 2015. PMID: 26276629 Free PMC article.
An apoptosis-dependent checkpoint for autoimmunity in memory B and plasma cells.
Mayer CT, Nieke JP, Gazumyan A, Cipolla M, Wang Q, Oliveira TY, Ramos V, Monette S, Li QZ, Gershwin ME, Kashkar H, Nussenzweig MC. Mayer CT, et al. Among authors: wang q. Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24957-24963. doi: 10.1073/pnas.2015372117. Epub 2020 Sep 22. Proc Natl Acad Sci U S A. 2020. PMID: 32963096 Free PMC article.
Structural basis for SARS-CoV-2 neutralizing antibodies with novel binding epitopes.
Fu D, Zhang G, Wang Y, Zhang Z, Hu H, Shen S, Wu J, Li B, Li X, Fang Y, Liu J, Wang Q, Zhou Y, Wang W, Li Y, Lu Z, Wang X, Nie C, Tian Y, Chen D, Wang Y, Zhou X, Wang Q, Yu F, Zhang C, Deng C, Zhou L, Guan G, Shao N, Lou Z, Deng F, Zhang H, Chen X, Wang M, Liu L, Rao Z, Guo Y. Fu D, et al. Among authors: wang x, wang w, wang y, wang m, wang q. PLoS Biol. 2021 May 7;19(5):e3001209. doi: 10.1371/journal.pbio.3001209. eCollection 2021 May. PLoS Biol. 2021. PMID: 33961621 Free PMC article.
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