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Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity.
Fang L, Hao Y, Yu H, Gu X, Peng Q, Zhuo H, Li Y, Liu Z, Wang J, Chen Y, Zhang J, Tian H, Gao Y, Gao R, Teng H, Shan Z, Zhu J, Li Z, Liu Y, Zhang Y, Yu F, Lin Z, Hao Y, Ge X, Yuan J, Hu HG, Ma Y, Qin HL, Wang P. Fang L, et al. Among authors: wang j, wang p. Cancer Cell. 2023 Jun 12;41(6):1118-1133.e12. doi: 10.1016/j.ccell.2023.05.005. Epub 2023 Jun 1. Cancer Cell. 2023. PMID: 37267951 Free article.
Ring domains are essential for GATOR2-dependent mTORC1 activation.
Jiang C, Dai X, He S, Zhou H, Fang L, Guo J, Liu S, Zhang T, Pan W, Yu H, Fu T, Li D, Inuzuka H, Wang P, Xiao J, Wei W. Jiang C, et al. Among authors: wang p. Mol Cell. 2023 Jan 5;83(1):74-89.e9. doi: 10.1016/j.molcel.2022.11.021. Epub 2022 Dec 16. Mol Cell. 2023. PMID: 36528027 Free PMC article.
Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Chen Y, Wu J, Zhai L, Zhang T, Yin H, Gao H, Zhao F, Wang Z, Yang X, Jin M, Huang B, Ding X, Li R, Yang J, He Y, Wang Q, Wang W, Kloeber JA, Li Y, Hao B, Zhang Y, Wang J, Tan M, Li K, Wang P, Lou Z, Yuan J. Chen Y, et al. Among authors: wang w, wang z, wang j, wang p, wang q. Cell. 2024 Jan 18;187(2):294-311.e21. doi: 10.1016/j.cell.2023.11.022. Epub 2023 Dec 20. Cell. 2024. PMID: 38128537
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