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Glycoengineering of Antibodies for Modulating Functions.
Wang LX, Tong X, Li C, Giddens JP, Li T. Wang LX, et al. Annu Rev Biochem. 2019 Jun 20;88:433-459. doi: 10.1146/annurev-biochem-062917-012911. Epub 2019 Mar 27. Annu Rev Biochem. 2019. PMID: 30917003 Free PMC article. Review.
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator.
Chiang MJ, Holbert MA, Kalin JH, Ahn YH, Giddens J, Amin MN, Taylor MS, Collins SL, Chan-Li Y, Waickman A, Hsiao PY, Bolduc D, Leahy DJ, Horton MR, Wang LX, Powell JD, Cole PA. Chiang MJ, et al. Among authors: wang lx. J Am Chem Soc. 2014 Mar 5;136(9):3370-3. doi: 10.1021/ja5006674. Epub 2014 Feb 24. J Am Chem Soc. 2014. PMID: 24533830 Free PMC article.
Chemoenzymatic Fc glycosylation via engineered aldehyde tags.
Smith EL, Giddens JP, Iavarone AT, Godula K, Wang LX, Bertozzi CR. Smith EL, et al. Among authors: wang lx. Bioconjug Chem. 2014 Apr 16;25(4):788-95. doi: 10.1021/bc500061s. Epub 2014 Apr 7. Bioconjug Chem. 2014. PMID: 24702330 Free PMC article.
Sialylation of IgG Fc domain impairs complement-dependent cytotoxicity.
Quast I, Keller CW, Maurer MA, Giddens JP, Tackenberg B, Wang LX, Münz C, Nimmerjahn F, Dalakas MC, Lünemann JD. Quast I, et al. Among authors: wang lx. J Clin Invest. 2015 Nov 2;125(11):4160-70. doi: 10.1172/JCI82695. Epub 2015 Oct 5. J Clin Invest. 2015. PMID: 26436649 Free PMC article. Clinical Trial.
1,527 results