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Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Bu P, Chen KY, Xiang K, Johnson C, Crown SB, Rakhilin N, Ai Y, Wang L, Xi R, Astapova I, Han Y, Li J, Barth BB, Lu M, Gao Z, Mines R, Zhang L, Herman M, Hsu D, Zhang GF, Shen X. Bu P, et al. Among authors: wang l. Cell Metab. 2018 Jun 5;27(6):1249-1262.e4. doi: 10.1016/j.cmet.2018.04.003. Epub 2018 Apr 26. Cell Metab. 2018. PMID: 29706565 Free PMC article.
A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells.
Bu P, Chen KY, Chen JH, Wang L, Walters J, Shin YJ, Goerger JP, Sun J, Witherspoon M, Rakhilin N, Li J, Yang H, Milsom J, Lee S, Zipfel W, Jin MM, Gümüş ZH, Lipkin SM, Shen X. Bu P, et al. Among authors: wang l. Cell Stem Cell. 2013 May 2;12(5):602-15. doi: 10.1016/j.stem.2013.03.002. Cell Stem Cell. 2013. PMID: 23642368 Free PMC article.
miR-1269 promotes metastasis and forms a positive feedback loop with TGF-β.
Bu P, Wang L, Chen KY, Rakhilin N, Sun J, Closa A, Tung KL, King S, Kristine Varanko A, Xu Y, Huan Chen J, Zessin AS, Shealy J, Cummings B, Hsu D, Lipkin SM, Moreno V, Gümüş ZH, Shen X. Bu P, et al. Among authors: wang l. Nat Commun. 2015 Apr 15;6:6879. doi: 10.1038/ncomms7879. Nat Commun. 2015. PMID: 25872451 Free PMC article.
Comprehensive models of human primary and metastatic colorectal tumors in immunodeficient and immunocompetent mice by chemokine targeting.
Chen HJ, Sun J, Huang Z, Hou H Jr, Arcilla M, Rakhilin N, Joe DJ, Choi J, Gadamsetty P, Milsom J, Nandakumar G, Longman R, Zhou XK, Edwards R, Chen J, Chen KY, Bu P, Wang L, Xu Y, Munroe R, Abratte C, Miller AD, Gümüş ZH, Shuler M, Nishimura N, Edelmann W, Shen X, Lipkin SM. Chen HJ, et al. Among authors: wang l. Nat Biotechnol. 2015 Jun;33(6):656-60. doi: 10.1038/nbt.3239. Epub 2015 May 25. Nat Biotechnol. 2015. PMID: 26006007 Free PMC article.
A recellularized human colon model identifies cancer driver genes.
Chen HJ, Wei Z, Sun J, Bhattacharya A, Savage DJ, Serda R, Mackeyev Y, Curley SA, Bu P, Wang L, Chen S, Cohen-Gould L, Huang E, Shen X, Lipkin SM, Copeland NG, Jenkins NA, Shuler ML. Chen HJ, et al. Among authors: wang l. Nat Biotechnol. 2016 Aug;34(8):845-51. doi: 10.1038/nbt.3586. Epub 2016 Jul 11. Nat Biotechnol. 2016. PMID: 27398792 Free PMC article.
Asymmetric division: An antitumor player?
Wang L, Bu P, Shen X. Wang L, et al. Mol Cell Oncol. 2016 May 19;3(4):e1164279. doi: 10.1080/23723556.2016.1164279. eCollection 2016 Jul. Mol Cell Oncol. 2016. PMID: 27652318 Free PMC article.
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