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GSK2795039 prevents RIP1-RIP3-MLKL-mediated cardiomyocyte necroptosis in doxorubicin-induced heart failure through inhibition of NADPH oxidase-derived oxidative stress.
Zhang XJ, Li L, Wang AL, Guo HX, Zhao HP, Chi RF, Xu HY, Yang LG, Li B, Qin FZ, Wang JP. Zhang XJ, et al. Among authors: wang al, wang jp. Toxicol Appl Pharmacol. 2023 Mar 15;463:116412. doi: 10.1016/j.taap.2023.116412. Epub 2023 Feb 9. Toxicol Appl Pharmacol. 2023. PMID: 36764612 Free article.
NADPH oxidase 2 mediates cardiac sympathetic denervation and myocyte autophagy, resulting in cardiac atrophy and dysfunction in doxorubicin-induced cardiomyopathy.
Ma Y, Zhao HP, Yang LG, Li L, Wang AL, Zhang XJ, Wang K, Yang B, Zhu ZF, Zhang PJ, Wang JP, Chi RF, Li B, Qin FZ, Wang ZP. Ma Y, et al. Among authors: wang al, wang k, wang jp, wang zp. Sci Rep. 2024 Mar 23;14(1):6971. doi: 10.1038/s41598-024-57090-2. Sci Rep. 2024. PMID: 38521855 Free PMC article.
1,626 results