Wang HR - Search Results

1

Themis suppresses the effector function of CD8⁺ T cells in acute viral infection.

Tang J, Jia X, Li J, Dong J, Wang J, Li W, Zhu Y, Hu Y, Hou B, Lin C, Cong Y, Ren T, Yan C, Yang H, Lai Q, Zheng H, Bao Y, Gautam N, Wang HR, Xu B, Chen XL, Li Q, Gascoigne NRJ, Fu G. Tang J, et al. Among authors: wang j, wang hr. Cell Mol Immunol. 2023 May;20(5):512-524. doi: 10.1038/s41423-023-00997-z. Epub 2023 Mar 28. Cell Mol Immunol. 2023. PMID: 36977779 Free PMC article.

2

Monoubiquitination of p120-catenin is essential for TGFβ-induced epithelial-mesenchymal transition and tumor metastasis.

Wu Q, Li G, Wen C, Zeng T, Fan Y, Liu C, Fu GF, Xie C, Lin Q, Xie L, Huang L, Pu P, Ouyang Z, Chan HL, Zhao TJ, Chen XL, Fu G, Wang HR. Wu Q, et al. Among authors: wang hr. Sci Adv. 2020 Jan 22;6(4):eaay9819. doi: 10.1126/sciadv.aay9819. eCollection 2020 Jan. Sci Adv. 2020. PMID: 32010791 Free PMC article.

3

Themis is indispensable for IL-2 and IL-15 signaling in T cells.

Liu Y, Cong Y, Niu Y, Yuan Y, Tan F, Lai Q, Hu Y, Hou B, Li J, Lin C, Zheng H, Dong J, Tang J, Chen Q, Brzostek J, Zhang X, Chen XL, Wang HR, Gascoigne NRJ, Xu B, Lin SH, Fu G. Liu Y, et al. Among authors: wang hr. Sci Signal. 2022 Feb 15;15(721):eabi9983. doi: 10.1126/scisignal.abi9983. Epub 2022 Feb 15. Sci Signal. 2022. PMID: 35167340

4

TMEM25 inhibits monomeric EGFR-mediated STAT3 activation in basal state to suppress triple-negative breast cancer progression.

Bi J, Wu Z, Zhang X, Zeng T, Dai W, Qiu N, Xu M, Qiao Y, Ke L, Zhao J, Cao X, Lin Q, Chen XL, Xie L, Ouyang Z, Guo J, Zheng L, Ma C, Guo S, Chen K, Mo W, Fu G, Zhao TJ, Wang HR. Bi J, et al. Among authors: wang hr. Nat Commun. 2023 Apr 24;14(1):2342. doi: 10.1038/s41467-023-38115-2. Nat Commun. 2023. PMID: 37095176 Free PMC article.

5

SHP-1 Regulates CD8+ T Cell Effector Function but Plays a Subtle Role with SHP-2 in T Cell Exhaustion Due to a Stage-Specific Nonredundant Functional Relay.

Hou B, Hu Y, Zhu Y, Wang X, Li W, Tang J, Jia X, Wang J, Cong Y, Quan M, Yang H, Zheng H, Bao Y, Chen XL, Wang HR, Xu B, Gascoigne NRJ, Fu G. Hou B, et al. Among authors: wang x, wang j, wang hr. J Immunol. 2024 Feb 1;212(3):397-409. doi: 10.4049/jimmunol.2300462. J Immunol. 2024. PMID: 38088801

6

Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.

Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, Hong L, Xie C, Li X, Zhao H, Liu Q, Jiang M, Chen Q, Zhang J, Li Y, Song S, Wang HR, Zhou R, Johnson RL, Chien KY, Lin SC, Han J, Avruch J, Chen L, Zhou D. Geng J, et al. Among authors: wang x, wang p, wang hr. Nat Immunol. 2015 Nov;16(11):1142-52. doi: 10.1038/ni.3268. Epub 2015 Sep 28. Nat Immunol. 2015. PMID: 26414765 Free PMC article.

7

Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.

Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, Song S, Wang H, Chen L, Zhou D, Liu Q, Ren R, Zhang J, Deng X. Jiang J, et al. Cancer Res. 2017 Jan 1;77(1):175-186. doi: 10.1158/0008-5472.CAN-16-1038. Epub 2016 Oct 10. Cancer Res. 2017. PMID: 27758886

8

The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity.

Tang WS, Weng L, Wang X, Liu CQ, Hu GS, Yin ST, Tao Y, Hong NN, Guo H, Liu W, Wang HR, Zhao TJ. Tang WS, et al. Among authors: wang x, wang hr. Cell Rep. 2021 Jul 6;36(1):109314. doi: 10.1016/j.celrep.2021.109314. Cell Rep. 2021. PMID: 34233190 Free article.

9

ATR/Chk1 signaling induces autophagy through sumoylated RhoB-mediated lysosomal translocation of TSC2 after DNA damage.

Liu M, Zeng T, Zhang X, Liu C, Wu Z, Yao L, Xie C, Xia H, Lin Q, Xie L, Zhou D, Deng X, Chan HL, Zhao TJ, Wang HR. Liu M, et al. Among authors: wang hr. Nat Commun. 2018 Oct 8;9(1):4139. doi: 10.1038/s41467-018-06556-9. Nat Commun. 2018. PMID: 30297842 Free PMC article.

10

A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.

Tian M, Zeng T, Liu M, Han S, Lin H, Lin Q, Li L, Jiang T, Li G, Lin H, Zhang T, Kang Q, Deng X, Wang HR. Tian M, et al. Among authors: wang hr. J Biol Chem. 2019 Feb 22;294(8):2880-2891. doi: 10.1074/jbc.RA118.003822. Epub 2018 Dec 26. J Biol Chem. 2019. PMID: 30587574 Free PMC article.

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