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A live attenuated virus-based intranasal COVID-19 vaccine provides rapid, prolonged, and broad protection against SARS-CoV-2.
Chen J, Wang P, Yuan L, Zhang L, Zhang L, Zhao H, Chen C, Wang X, Han J, Chen Y, Jia J, Lu Z, Hong J, Lu Z, Wang Q, Chen R, Qi R, Ma J, Zhou M, Yu H, Zhuang C, Liu X, Han Q, Wang G, Su Y, Yuan Q, Cheng T, Wu T, Ye X, Zhang T, Li C, Zhang J, Zhu H, Chen Y, Chen H, Xia N. Chen J, et al. Among authors: wang x, wang g, wang p, wang q. Sci Bull (Beijing). 2022 Jul 15;67(13):1372-1387. doi: 10.1016/j.scib.2022.05.018. Epub 2022 May 26. Sci Bull (Beijing). 2022. PMID: 35637645 Free PMC article.
A multimechanistic antibody targeting the receptor binding site potently cross-protects against influenza B viruses.
Shen C, Chen J, Li R, Zhang M, Wang G, Stegalkina S, Zhang L, Chen J, Cao J, Bi X, Anderson SF, Alefantis T, Zhang M, Cai X, Yang K, Zheng Q, Fang M, Yu H, Luo W, Zheng Z, Yuan Q, Zhang J, Wai-Kuo Shih J, Kleanthous H, Chen H, Chen Y, Xia N. Shen C, et al. Among authors: wang g. Sci Transl Med. 2017 Oct 18;9(412):eaam5752. doi: 10.1126/scitranslmed.aam5752. Sci Transl Med. 2017. PMID: 29046433
An IgM antibody targeting the receptor binding site of influenza B blocks viral infection with great breadth and potency.
Shen C, Zhang M, Chen Y, Zhang L, Wang G, Chen J, Chen S, Li Z, Wei F, Chen J, Yang K, Guo S, Wang Y, Zheng Q, Yu H, Luo W, Zhang J, Chen H, Chen Y, Xia N. Shen C, et al. Among authors: wang g, wang y. Theranostics. 2019 Jan 1;9(1):210-231. doi: 10.7150/thno.28434. eCollection 2019. Theranostics. 2019. PMID: 30662563 Free PMC article.
Structures of pseudorabies virus capsids.
Wang G, Zha Z, Huang P, Sun H, Huang Y, He M, Chen T, Lin L, Chen Z, Kong Z, Que Y, Li T, Gu Y, Yu H, Zhang J, Zheng Q, Chen Y, Li S, Xia N. Wang G, et al. Nat Commun. 2022 Mar 22;13(1):1533. doi: 10.1038/s41467-022-29250-3. Nat Commun. 2022. PMID: 35318331 Free PMC article.
Protective anti-gB neutralizing antibodies targeting two vulnerable sites for EBV-cell membrane fusion.
Zhang X, Hong J, Zhong L, Wu Q, Zhang S, Zhu Q, Chen H, Wei D, Li R, Zhang W, Zhang X, Wang G, Zhou X, Chen J, Kang Y, Zha Z, Duan X, Huang Y, Sun C, Kong X, Zhou Y, Chen Y, Ye X, Feng Q, Li S, Xiang T, Gao S, Zeng MS, Zheng Q, Chen Y, Zeng YX, Xia N, Xu M. Zhang X, et al. Among authors: wang g. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2202371119. doi: 10.1073/pnas.2202371119. Epub 2022 Aug 2. Proc Natl Acad Sci U S A. 2022. PMID: 35917353 Free PMC article.
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